# Safety evaluation of percutaneous intrauterine hydrodissection in microwave ablation of uterine fibroids adjacent to the endometrium

## TL;DR

This study shows that using hydrodissection during microwave ablation of uterine fibroids safely protects the endometrium and improves symptoms in most patients.

## Contribution

The study introduces and validates percutaneous intrauterine hydrodissection as a novel protective method during microwave ablation of uterine fibroids.

## Key findings

- Hydrodissection fluid did not reflux into the pelvic cavity during or after ablation.
- Symptoms improved in 69.2% of patients with fibroid-related symptoms.
- No infertility cases were reported due to endometrial injury or intrauterine adhesion.

## Abstract

To assess the safety and efficacy of percutaneous intrauterine hydrodissection as a protective technique during microwave ablation (MWA) of uterine fibroids adjacent to the endometrium.

A retrospective analysis was conducted on patients who underwent MWA with the percutaneous intrauterine hydrodissection strategy. The distribution of isolating fluid, the protective effect of intrauterine hydrodissection, its influence on ablation efficacy, and potential complications were assessed.

A total of 32 female patients were enrolled in the present study. The median age of the patients was 45 years old, with the median target uterine fibroid maximum diameter of 6.9 cm. Thirteen patients presented with fibroid-related symptoms. No evidence of fluid reflux into the pelvic cavity was detected during and after ablation on either CEUS or CT imaging. No case of residual tumor, infection, endometriosis, intestinal injury or bladder injury was observed during follow-up. Symptom improvement was observed in 69.2% (9/13) patients. No patient reported infertility due to intrauterine adhesion or endometrial injury after ablation.

Percutaneous intrauterine hydrodissection is a safe and effective method for protecting endometrium during MWA of uterine fibroids adjacent to the endometrium.