# Ciprofloxacin-Imprinted Polymers: Synthesis, Characterization, and Applications

## TL;DR

This review discusses the synthesis, characterization, and applications of ciprofloxacin-imprinted polymers for selective recognition and removal of the antibiotic.

## Contribution

The paper provides a comprehensive analysis of recent advances in ciprofloxacin-imprinted polymer synthesis and applications.

## Key findings

- Ciprofloxacin-imprinted polymers show promise for selective separation and removal from environmental samples.
- Advanced imprinting techniques like nano-scale and electrochemical methods are highlighted for improved performance.
- Applications include HPLC stationary phases, drug release, and photocatalysis.

## Abstract

Ciprofloxacin, being a widely used antibiotic agent, has sparked growing interest in the field of molecularly imprinted polymers (MIP) for its selective recognition and removal. This review provides a comprehensive analysis of the recent advances in the synthesis and applications of ciprofloxacin-imprinted polymers. The examination of synthesis compositions for the preparation of these polymers includes thorough discussions on functional monomers, crosslinkers, initiators, and solid supports. Various imprinting techniques, including bulk, precipitation, co-precipitation, and surface polymerization, have been assessed for the fabrication of the imprinted polymers. Furthermore, the advancing imprinting techniques, encompassing nano-scale imprinting, multi-functional monomers, multi-template imprinting, and electrochemical imprinting, are also highlighted. Additionally, an extensive exploration of the diverse applications of these polymers is also presented. These applications encompass selective separation and removal of ciprofloxacin from environmental samples, visual and electrochemical detection in complex matrices, their use as a stationary phase for HPLC, drug release, and photocatalysis. This review offers valuable insights into the current advancements and potential future directions in the development of ciprofloxacin-imprinted polymers, emphasizing their importance in diverse analytical and environmental applications.