# Recent Advances in Fluorinated Colloidal Nanosystems for Biological Detection and Surface Coating

**Authors:** Fei Xu, Xiaolong Cao, Kai Yan

PMC · DOI: 10.3390/polym18030316 · Polymers · 2026-01-24

## TL;DR

This paper reviews recent progress in fluorinated nanosystems for biomedical imaging and surface coatings, highlighting their benefits and future potential.

## Contribution

The paper provides a comprehensive overview of recent advances and applications of fluorinated colloidal nanosystems in biological detection and surface coating.

## Key findings

- Fluorinated nanosystems show high specificity and biocompatibility for 19F MRI and biological detection.
- They offer unique advantages for surface coatings, including self-cleaning, antibacterial, and oil–water separation properties.
- Current challenges and future research directions in fluorinated nanosystem development are identified.

## Abstract

Fluorinated colloidal nanosystems have attracted significant attention for their advantageous properties and potential applications in the biomedical field, especially in 19F magnetic resonance imaging. These nanosystems are known for their high specificity, excellent biocompatibility, and ease of functional modification. Furthermore, they offer unique advantages for functional surface coating due to their surface performance and chemical resistance. This paper discusses recent developments in fluorinated colloidal nanosystems, including applications in biological detection (such as enzymes, proteins, pH levels, ions, reducing environments, and reactive oxygen species) and surface coating (such as self-cleaning, self-healing, antibacterial properties, anti-fogging, antifouling, and oil–water separation). This article also highlights current challenges and provides suggestions for future research directions in the field of fluorinated colloidal nanosystems.

## Full-text entities

- **Chemicals:** water (MESH:D014867), reactive oxygen species (MESH:D017382), oil (MESH:D009821)

## Full text

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## Figures

11 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12899710/full.md

## References

53 references — full list in the complete paper: https://tomesphere.com/paper/PMC12899710/full.md

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Source: https://tomesphere.com/paper/PMC12899710