# Breast Adenoid Cystic Carcinoma: Recognizing a Rare Pathological Diagnosis

**Authors:** Prajakta Attarde, Shital Parekh

PMC · DOI: 10.7759/cureus.101447 · Cureus · 2026-01-13

## TL;DR

This paper presents a rare case of breast adenoid cystic carcinoma and highlights its unique features and management.

## Contribution

The paper contributes a documented case of ACC in the breast and emphasizes its diagnostic and clinical significance.

## Key findings

- ACC of the breast is rare and has a distinct dual cell population.
- Despite a triple-negative immunophenotype, ACC has a favorable prognosis.
- A multidisciplinary approach is necessary for managing ACC cases.

## Abstract

Adenoid cystic carcinoma (ACC) of the breast is an exceedingly rare neoplasm. It exhibits a distinct dual cell population and a favorable prognosis despite its often triple-negative immunophenotype. We present a rare case of ACC diagnosed on core needle biopsy and confirmed in the resection specimen. The histopathological features, immunohistochemical profile, and relevant literature are discussed. This case emphasizes the importance of recognizing this rare entity when encountered in breast biopsies and the necessity for a collaborative, multidisciplinary approach to management.

## Linked entities

- **Diseases:** adenoid cystic carcinoma (MONDO:0004971), breast cancer (MONDO:0004989)

## Full-text entities

- **Diseases:** neoplasm (MESH:D009369), Breast Adenoid Cystic Carcinoma (MESH:D005348), ACC (MESH:D003528)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12899309/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12899309/full.md

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Source: https://tomesphere.com/paper/PMC12899309