# Severe Transaminitis in a Patient With Influenza: A Case Report

**Authors:** Daniel Rossie, Emmelyn Samones, Deena Bengiamin

PMC · DOI: 10.7759/cureus.101449 · Cureus · 2026-01-13

## TL;DR

This case report highlights a rare complication of influenza, severe liver enzyme elevation, and the need for further research on its clinical significance.

## Contribution

The report emphasizes the under-recognized complication of transaminitis in influenza and calls for further evaluation.

## Key findings

- Influenza can cause severe transaminitis and rhabdomyolysis.
- Patients with influenza and transaminitis have higher mortality rates.
- Routine lab testing for viral syndromes is often not performed, limiting data on such complications.

## Abstract

We present a case of a patient with significant liver function test (LFT) elevation and rhabdomyolysis in the setting of influenza infection. Patients with influenza infection and transaminitis have a higher mortality rate. There is limited data on the incidence of this complication, as routine laboratory values are not obtained in the emergency department for viral syndromes. Our patient had multiple reasons for transaminitis, including rhabdomyolysis, influenza infection, and possible acetaminophen toxicity. Our case report brings to light a potential complication of influenza infection, transaminitis, and the need for further evaluation to determine its clinical significance.

## Linked entities

- **Chemicals:** acetaminophen (PubChem CID 1983)
- **Diseases:** influenza (MONDO:0005812), rhabdomyolysis (MONDO:0005290)

## Full-text entities

- **Diseases:** Influenza (MESH:D007251), rhabdomyolysis (MESH:D012206), toxicity (MESH:D064420)
- **Chemicals:** acetaminophen (MESH:D000082)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12899307/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12899307/full.md

---
Source: https://tomesphere.com/paper/PMC12899307