# Exploring the Balance Between Artificial Intelligence and Human Expertise in Shaping Breast Reconstruction Outcomes: A Comparative Reflection Study

**Authors:** Ioan Constantin Pop, Maximilian Vlad Muntean, Vlad Alexandru Gata, Radu Alexandru Ilies, Delia Nicoara, Claudiu Ioan Filip, Vasile Pop, Patriciu Andrei Achimas-Cadariu

PMC · DOI: 10.3390/jcm15031170 · Journal of Clinical Medicine · 2026-02-02

## TL;DR

This study compares AI and surgeon responses to patient questions about breast reconstruction, finding AI provides mostly accurate and helpful answers.

## Contribution

The study evaluates AI's performance in counseling patients on breast reconstruction, a previously underexplored area.

## Key findings

- AI responses scored an average of 3.1 out of 4 for accuracy and completeness.
- AI performed better in reconstruction options and postoperative care than in oncological justification.
- No AI response was deemed unsatisfactory, and 15% were rated excellent.

## Abstract

Background/Objectives: Artificial intelligence (AI) has shown potential in patient education and integration into clinical decision support systems. However, its performance in counseling patients on breast reconstruction currently remains underexplored. This study’s objective is to compare AI-generated answers with expert surgeon responses to common patient questions (derived from clinical scenarios) in domains like oncological justification, reconstructive options, and postoperative care. Methods: We realized an observer-blinded study using five real-world clinical scenarios in the field of oncologic and reconstructive surgery of the breast. Both ChatGPT-5 (October 2025 version) and a senior board-certified plastic surgeon responded to frequently asked questions, which were split into three domains: (1) oncological and surgical justification; (2) reconstruction options and outcomes, respectively; and (3) postoperative period. The answers were evaluated by another senior plastic surgeon using a four-grade ordinal scoring system (1 = unsatisfactory, 4 = excellent), which assessed accuracy, completeness, safety, nuance, and alignment with the current guidelines. Results: Across a total of 40 questions, the average AI response score was 3.1 ± 0.6. Domain-specific items scored lowest values for oncological justification (2.8 ± 0.7) and higher values for reconstruction options/outcomes and postoperative care (both 3.2 ± 0.4). No AI response was graded as unsatisfactory (score 1). Responses graded 4 (15%) were considered comprehensive, accurate, and patient-friendly. Conclusions: Globally, ChatGPT-5 provides satisfactory, readable, and medically accurate answers to basic patient questions on breast reconstruction, with a few limitations in nuanced oncological justification.

## Linked entities

- **Diseases:** breast cancer (MONDO:0004989)

## Full-text entities

- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC12898539/full.md

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Source: https://tomesphere.com/paper/PMC12898539