# The Presentation and Treatment of Myointimoma: A Systematic Review and the First Case Report of Penile Myointimoma as a Cause of Urethral Obstruction

**Authors:** Deirdre Maria König-Castillo, Armin Henning, Richard Wasicky, Clemens Kinsky, H. Christoph Klingler, Eva M. Compérat

PMC · DOI: 10.3390/jcm15031130 · Journal of Clinical Medicine · 2026-02-01

## TL;DR

This paper reviews myointimoma, a rare benign tumor of the penis, and reports a new case causing urethral blockage.

## Contribution

The first case report of penile myointimoma causing urethral obstruction is presented.

## Key findings

- Only 30 cases of myointimoma have been reported, all near the glans penis.
- Myointimoma should be considered in cases of recurring bladder outlet obstruction.
- A 33-year-old male presented with urethral stricture without known risk factors.

## Abstract

Background/Objectives: Myointimoma is a rare, benign soft tissue tumor of the penis. We present a systematic review of the current literature and a case report of a 33-year-old male with a urethral stricture without discernible risk factors. Our aim was to investigate current knowledge on Myointimomas and increase the awareness of this entity. Methods: A systematic literature search was conducted across EMBASE, MEDLINE, PubMed, Scopus, Web of Science, and Google Scholar. Only 30 previously reported cases of this tumor are known—all located at the glans penis or in close proximity to it. Results: After the exclusion of non-eligible studies, 14 studies were included. Conclusions: Myointimomas are a relevant differential diagnosis in recurring cases of bladder outlet obstruction.

## Linked entities

- **Diseases:** urethral obstruction (MONDO:0001556), urethral stricture (MONDO:0002127)

## Full-text entities

- **Diseases:** urethral stricture (MESH:D014525), bladder outlet obstruction (MESH:D001748), Penile (MESH:D010409), tissue tumor (MESH:D009369), Urethral Obstruction (MESH:D014524)

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12897719/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12897719/full.md

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Source: https://tomesphere.com/paper/PMC12897719