# From Annotation to Prediction: Hospital-Grade Early Seizure Risk Prediction from Adult EEG

## TL;DR

This paper presents an AI model that predicts early seizure risk in adults using EEG data, aiming to improve diagnostic efficiency and accuracy in clinical settings.

## Contribution

The study introduces a novel AI-based approach for early seizure risk prediction by focusing on interictal EEG patterns rather than ictal states.

## Key findings

- The Random Forest algorithm achieved 96.50% accuracy in identifying normal EEG activity.
- The model can classify abnormal EEGs into three clinically relevant categories.
- The AI system improves efficiency and accessibility of EEG interpretation, especially in resource-limited settings.

## Abstract

Background: Manual review of EEG recordings in clinical settings is inherently time-consuming and labor-intensive. These challenges highlight a pressing need for automated EEG analysis tools capable of supporting clinicians by improving efficiency and diagnostic accuracy. Objectives: This study aims to develop and validate an AI-based model for the automated interpretation of adult EEG recordings. Unlike previous approaches that emphasize seizure detection during ictal states, our model targets the early prediction of seizure risk through systematic annotation and recognition of interictal patterns. Methods: The model is designed to accurately distinguish between normal and abnormal EEGs, encompassing both interictal and ictal activity. Abnormal EEGs will be further classified into three clinically relevant categories: (1) non-epileptiform abnormalities such as focal or diffuse slowing, (2) epileptiform discharges, and (3) electrographic seizures. Three AI-based classification algorithms were implemented: Support Vector Machine (SVM), Random Forest (RF), and K-Nearest Neighbors (KNN). Results: RF demonstrated optimal performance across most tasks, achieving 96.50% accuracy for normal activity identification. This AI-driven system enhances the efficiency, consistency, and accessibility of EEG interpretation. It is particularly valuable in settings with limited access to neurophysiologists and offers an innovative approach to improving diagnostic timelines and clinical decision-making. Conclusions: Ultimately, this tool will support physicians in diagnosing neurological conditions and monitoring patient progress over time.