# Development of a Computer Program for Determining the Dose of Laser Radiation (860 nm) Received by Tumor and Breast Tissue

## TL;DR

A computer program was developed to calculate the laser radiation dose absorbed by breast tissue and tumors using optical modeling and diagnostic imaging data.

## Contribution

A new method and computer program were developed to accurately determine laser radiation doses in breast tissue using optical modeling and medical imaging.

## Key findings

- Attenuation and scattering coefficients for breast tissue were experimentally measured.
- A computer program was created to calculate laser doses using a multilayer scattering optical model.
- The method integrates objective imaging data to determine optimal laser irradiation modes.

## Abstract

LLLT is a non-invasive treatment method for various pathologies based on the exposure of target tissues to an 860–910 nm laser beam. This approach has proven effective both as a standalone treatment and when combined with other therapeutic modalities. However, determining the exact dose of laser radiation absorbed by target tissue has remained challenging. Leading medical and technical organizations in the Russian Federation conducted experimental measurements of angular intensity distribution to determine attenuation and scattering coefficients for breast tissue. This substantially improved the accuracy of assessing laser radiation doses absorbed by both pathological breast tissue and surrounding tissues. Based on this research, a method was developed for determining the absorbed dose of laser radiation by the tumor based on objective examination of breast tissue (ultrasound, mammography, CT, and MRI). A computer program was developed to calculate the laser dose delivered to target tissues using an optical model of a multilayer scattering medium.

Laser therapy (860–910 nm) has been used to treat cancer since 1988. A key challenge is determining the dose of laser radiation absorbed by the tumor. Attenuation coefficients of laser radiation were determined for different breast tissues at various tissue thicknesses and beam angles. These results enable the development of a methodology for determining optimal irradiation modes by considering both the absorbed dose of laser radiation and objective examination data (ultrasound, mammography, CT, and MRI).