# Integrating Cardiopulmonary Exercise Testing in the Assessment of Aortic Stenosis: A Comprehensive Review

**Authors:** Peter Luke, Helen Banks, Christopher Eggett

PMC · DOI: 10.3390/healthcare14030329 · Healthcare · 2026-01-28

## TL;DR

This paper reviews how cardiopulmonary exercise testing can help assess and manage aortic stenosis, a serious heart valve condition.

## Contribution

The paper provides a comprehensive review of the role of cardiopulmonary exercise testing in aortic stenosis risk stratification.

## Key findings

- Aortic stenosis is a severe valve disease with high mortality if untreated.
- Cardiopulmonary exercise testing is a safe and effective tool for managing aortic stenosis.
- The test is underused due to patient frailty and comorbidities.

## Abstract

Aortic stenosis is a progressive and insidious form of valve disease with a high mortality if left untreated. While cardiopulmonary exercise testing is recognised as a safe and effective strategy to aid in the management and timing of valvular intervention, it is often underused due to patient frailty and concomitant comorbidities. This study discusses the pathophysiology of aortic stenosis and current evidence supporting the use of cardiopulmonary exercise testing for the risk stratification and management of aortic stenosis.

## Linked entities

- **Diseases:** aortic stenosis (MONDO:0042981)

## Full-text entities

- **Diseases:** Aortic Stenosis (MESH:D001024), valve disease (MESH:D006349)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12897064/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12897064/full.md

## References

66 references — full list in the complete paper: https://tomesphere.com/paper/PMC12897064/full.md

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Source: https://tomesphere.com/paper/PMC12897064