Correction: Golubovskaya et al. Gene Expression Profiling Identifies Important Genes Affected by R2 Compound Disrupting FAK and P53 Complex. Cancers 2014, 6, 166–178
Vita M. Golubovskaya, Baotran Ho, Jeffrey Conroy, Song Liu, Dan Wang, William G. Cance
Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsRetinoids in leukemia and cellular processes · Cancer-related Molecular Pathways · Cell Adhesion Molecules Research
In the original publication [1], there was a mistake in Figure 3A as published. The two colony images in the lower panel were similar. The corrected Figure 3A appears below.
The corresponding Figure 3 legend has been updated to reflect the removal of some of the clonogenic assays.
The text in Section 2.2 The R2 Sensitized Cancer Cells to M13 (Disrupting FAK and Mdm-2) and Nutlin-1 (Disrupting p53 and Mdm-2) Treatments, paragraph 2 has been updated to ‘Since Nutlin-1 that disrupts p53 and Mdm-2 protein interaction [15], also can induce p53, we treated HCT116 p53^+/+^ and HCT53^−/−^ cells with either R2 alone, Nutlin-1 alone or with combination of R2 and Nutlin-1 (Figure 3B)’.
The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.
The reference list from the paper itself. Each links out to its DOI / PubMed record.