# Empowering Women Through Pharmaceutical Education: A New Approach to Premenstrual Syndrome

**Authors:** Celia Piquer-Martínez, Manuel Gómez-Guzmán, Adriana González-Salgado, María Isabel Valverde-Merino, Francisco Javier Ferreira-Alfaya, Blete Isufi, Victoria García-Cárdenas, Francisco Rivas-García, María José Zarzuelo

PMC · DOI: 10.3390/healthcare14030348 · 2026-01-30

## TL;DR

A pharmacist-led education program significantly reduced premenstrual syndrome symptoms and improved quality of life for women in Spain.

## Contribution

This study introduces a novel pharmacist-led educational intervention using an infographic to manage premenstrual syndrome symptoms.

## Key findings

- Participants showed a significant reduction in pain intensity and improvements in irritability, insomnia, and fatigue.
- Quality of life improved, with fewer women reporting a negative impact after the intervention.
- Oral contraceptive use was found to be a protective factor against PMS symptoms.

## Abstract

Objective: To evaluate the effectiveness of a pharmacist-led educational intervention in reducing premenstrual syndrome (PMS) symptoms and improving self-care practices. Methods: A mixed-design study was conducted in community pharmacies in Spain between January and June 2025. First, a cross-sectional analysis determined PMS prevalence. Second, a longitudinal pre-post study was performed with women suffering from PMS. The intervention involved personalized guidance and an evidence-based educational infographic. Primary outcomes included symptom severity (measured by a numeric rating scale) and quality of life. Results: 350 women participated in the study. The mean age of participants was 23.7 ± 6.3 years (range: 17–51 years). At the six-month follow-up, the PMS group showed a significant reduction in mean pain intensity (from 6.86 to 3.26; p < 0.001) and a smaller reduction in the control group (from 4.82 to 2.88; p < 0.001), alongside improvements in irritability, insomnia, and fatigue. The proportion of women reporting a negative impact on quality of life decreased from 97.0% to 60.8% (p < 0.001). Oral contraceptive use was identified as a protective factor (OR: 0.33; 95% CI: 0.17–0.65). Conclusions: Educational interventions led by community pharmacists are effective in significantly alleviating PMS symptoms and enhancing women’s quality of life. Practice Implications: Community pharmacists are strategically positioned to identify women with PMS and provide evidence-based education. Implementing structured protocols and visual tools in pharmacies can optimize symptom management and promote self-care.

## Linked entities

- **Diseases:** premenstrual syndrome (MONDO:0004169)

## Full-text entities

- **Diseases:** irritability (MESH:D001523), PMS (MESH:D011293), fatigue (MESH:D005221), pain (MESH:D010146), insomnia (MESH:D007319)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12896598/full.md

---
Source: https://tomesphere.com/paper/PMC12896598