# Simplified Knee MRI ‘Sagittal Tibial Epi-Physis (STEP)’ Shorthand for Skeletal Age Assessment in Pediatric Patients with ACL Injury

**Authors:** Alberto Grassi, Claudio Rossi, Luca Ambrosini, Yuta Nakanishi, Emre Anil Ozbek, Amir Assaf, Hikaru Kayano, Mohammad Ibra Alhalalmeh, Kyle Borque, Stefano Zaffagnini

PMC · DOI: 10.3390/diagnostics16030442 · 2026-02-01

## TL;DR

A new MRI shorthand called STEP is developed to reliably assess skeletal age in children with ACL injuries, aiding surgical decisions.

## Contribution

The STEP Shorthand is a novel, simplified MRI-based method for skeletal age assessment in skeletally immature ACL patients.

## Key findings

- The STEP Shorthand showed strong correlation with chronological age (rho = 0.890) across sex subgroups.
- High inter-rater reliability was observed, comparable to existing MRI-based shorthand tools.
- The STEP method is reproducible and practical for use across varying levels of clinical expertise.

## Abstract

Objectives: To develop a simplified MRI-based shorthand assessment method, referred to as the Sagittal Tibial Epi-Physis (STEP) Shorthand, for skeletal age assessment in skeletally immature patients with anterior cruciate ligament (ACL) injuries. This study aimed to elaborate a single-plane MRI-based skeletal age estimation tool and to explore its feasibility and inter-rater reliability in comparison with existing MRI-based shorthands. Methods: This prospective study included 130 knee MRIs (79% males) from 97 skeletally immature patients (overall average age of 14.0 ± 2.1 years) with ACL injuries treated between February 2022 and January 2025. A new shorthand assessment method was developed based on sagittal T1-weighted MRI evaluation of the proximal tibial epiphysis. A validation cohort of 74 MRIs was independently evaluated by four raters with different levels of expertise using the STEP, Meza, and Politzer shorthand atlases. Inter-rater reliability (ICC), intra-rater agreement (Cohen’s kappa), and association with chronological age (Spearman rho) were calculated. Results: The STEP Shorthand tool demonstrated a strong association with chronological age (rho = 0.890, p < 0.001) with consistent associations across sex subgroups. Inter-rater reliability was high and comparable to established MRI-based shorthands. The use of a focused sagittal T1-weighted evaluation allowed for a simplified and reproducible assessment across raters with varying experience levels. Conclusions: The STEP Shorthand represents a pragmatic and reliable tool for MRI-based skeletal age assessment in pediatric and adolescent patients with ACL injuries. The STEP Shorthand can support timely decision-making in surgical planning and enhance standardization across different levels of clinical expertise.

## Full-text entities

- **Diseases:** ACL Injury (MESH:D000070598)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12896386/full.md

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Source: https://tomesphere.com/paper/PMC12896386