# Complete genomes of Phascolarctobacterium faecium isolates obtained from pediatric mucosal-luminal interface aspirate samples

**Authors:** Gillian Tanabe, David R. Mack, Alain Stintzi

PMC · DOI: 10.1128/mra.00789-25 · 2026-01-16

## TL;DR

This paper presents the full genome sequences of two gut bacteria strains from children, some of whom had Crohn’s disease.

## Contribution

The study provides the first complete genome sequences of P. faecium from pediatric mucosal-luminal interface samples.

## Key findings

- Two complete P. faecium genomes were sequenced from pediatric gut samples.
- The isolates were obtained from children with and without Crohn’s disease.

## Abstract

The bacterium Phascolarctobacterium faecium frequently colonizes the human gut and has been reported to have reduced abundance in people with Crohn’s disease. Here, we report the complete genome sequences of two P. faecium strains isolated from mucosal-luminal interface samples taken from pediatric participants with/without Crohn’s disease.

## Linked entities

- **Diseases:** Crohn’s disease (MONDO:0005011)
- **Species:** Phascolarctobacterium faecium (taxon 33025)

## Full-text entities

- **Diseases:** Crohn's disease (MESH:D003424)
- **Species:** Phascolarctobacterium faecium (species) [taxon 33025], Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12896173