# Comparative 16S rRNA profiling of broiler chicken cecal microbiota following Bacillus lipopeptide or enrofloxacin administration

## TL;DR

This study compares how a Bacillus lipopeptide and an antibiotic affect the gut microbiota of chickens using 16S rRNA sequencing.

## Contribution

The study provides novel insights into the microbial community shifts caused by a Bacillus lipopeptide versus enrofloxacin in broiler chickens.

## Key findings

- Peptide supplementation caused distinct microbial compositional shifts compared to antibiotic treatment.
- 16S rRNA sequencing revealed differences in cecal microbiota following Bacillus lipopeptide administration versus enrofloxacin.

## Abstract

We report 16S rRNA gene sequencing data characterizing the cecal microbiota of 35-day-old Ross 308 broiler chickens supplemented with a crude fraction of Bacillus subtilis GM5 lipopeptides in comparison with the fluoroquinolone antibiotic enrofloxacin. Microbial community analyses revealed distinct compositional shifts in response to peptide supplementation versus antibiotic treatment.