Enhancing Preoperative Orthopaedic Communication: A Comparative Analysis of Large Language Model- and Clinician-Generated Clinic Letters
Wilfred C Saunders, Alexander C Glendenning, Charles Gamble, Richard Roberts

TL;DR
This study compares clinic letters generated by large language models and clinicians, finding that LLMs produce more readable and understandable content while including essential medical information.
Contribution
The study demonstrates that large language models can enhance preoperative communication by generating more readable and informative clinic letters than clinicians.
Findings
LLM-generated letters had higher understandability scores and simpler readability levels compared to clinician letters.
OpenAI o1 achieved the highest complication profile compliance among all tested models.
LLMs can reduce administrative burdens and improve patient-centered decision-making in orthopaedic practice.
Abstract
Background Clear, effective communication is fundamental to orthopaedic practice, particularly when securing informed consent. Escalating NHS workforce and time constraints necessitate tools that streamline, yet enhance, patient‑clinician dialogue. By analysing understandability, readability, and complication profile inclusion, this study aims to determine the feasibility of large language model (LLM)‑assisted correspondence to support equitable, patient‑centred consent and decision‑making. Methods Six frequently performed orthopaedic operations were chosen. Standardised, clinic‑friendly prompts were fed to four LLMs: OpenAI o1, DeepSeek, Gemini, and Copilot, each producing two letters per procedure. An identical prompt was provided to two clinicians to produce letters for the same operation, serving as a human benchmark. Understandability (Patient Education Materials Assessment Tool…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsPatient-Provider Communication in Healthcare · Health Literacy and Information Accessibility · Total Knee Arthroplasty Outcomes
