# Experiences and Expectations of Hospitalised Patients Undergoing Negative Pressure Wound Therapy With Instillation: A Qualitative Study

**Authors:** Annabel Nanninga, Heleen Westland, Ricardo G. Orsini, Marja A. Boermeester, Anne M. Eskes, Hannah Groenen

PMC · DOI: 10.1111/scs.70203 · 2026-02-11

## TL;DR

Hospitalized patients using negative pressure wound therapy with instillation experience both physical and emotional impacts, highlighting the need for better preparation and nursing support.

## Contribution

This study provides novel qualitative insights into patient experiences and expectations with negative pressure wound therapy with instillation.

## Key findings

- Patients felt more confident with detailed explanations about the treatment device.
- Nurses' unfamiliarity with the therapy reduced patient trust.
- Improved wound healing increased patients' trust in the treatment.

## Abstract

Negative pressure wound therapy with instillation is increasingly used to treat various wounds. However, there is limited information about its impact on patient experiences. This study aims to explore the experiences of hospitalised patients undergoing negative pressure wound therapy with instillation for different types of wounds and to explore their expectations regarding continuing treatment at home.

We conducted a qualitative study using semi‐structured interviews. 12 patients treated with negative pressure wound therapy with instillation across various hospitals in the Netherlands were interviewed between January 2024 and June 2024. Data were analysed using Braun and Clarke's reflexive thematic analysis.

This study was deemed not subject to the Medical Research Involving Human Subjects Act (WMO), as confirmed by a non‐WMO declaration from the ethics committee. All participants provided informed consent prior to the interview.

Seven themes were generated from the data: feeling prepared for negative pressure wound therapy with instillation, gaining trust and hope because of wound healing, having trust in the expertise of nurses, facing fear and dread during negative pressure wound therapy with instillation, dealing with sleep disturbance, having difficulties with daily living activities, and worrying about undergoing negative pressure wound therapy with instillation at home. Although patients initially faced uncertainties, improved wound healing builds trust in the treatment.

Negative pressure wound therapy with instillation significantly impacts patients' physical and emotional well‐being. Patients felt more prepared and confident when provided with detailed explanations about the device and what to expect during treatment. Nurses' unfamiliarity with the treatment further diminished patient trust. For optimal patient care, patients require adequate preparation and support from well‐trained nurses to manage the physical and emotional impact of negative pressure wound therapy with instillation, in both hospital and home settings.

Adheres to the Reflexive Thematic Analysis Reporting Guidelines.

Patients were involved in the study through interviews.

## Full-text entities

- **Diseases:** sleep disturbance (MESH:D012893)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12895139/full.md

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Source: https://tomesphere.com/paper/PMC12895139