# From domination to partnership: Lab-trained microorganisms for environmental bioremediation

**Authors:** Victor de Lorenzo

PMC · DOI: 10.1038/s44319-025-00681-5 · 2026-01-03

## TL;DR

The paper argues for a new approach to using engineered microbes for cleaning up the environment, moving away from strict control to a more collaborative and responsible strategy.

## Contribution

The paper introduces a conceptual shift from containment to stewardship in the use of engineered microorganisms for bioremediation.

## Key findings

- Current regulatory frameworks for bioremediation are based on outdated containment principles.
- A care-based and culturally adjusted approach is proposed to better align biotechnology with ecological and societal needs.
- This shift is seen as essential for advancing responsible bioremediation practices.

## Abstract

Despite advances in synthetic biology and ecological understanding, the deployment of engineered microorganisms for bioremediation remains stalled due to outdated containment-centric narratives and regulatory frameworks. A shift from a logic of control to one of care and stewardship, is needed for a more responsible, culturally adjusted and scientifically grounded path toward leveraging biotechnology for planetary repair.

## Full-text entities

- **Diseases:** paralysis (MESH:D010243)
- **Chemicals:** CO2 (MESH:D002245), heavy metals (MESH:D019216), polyfluorinated chemicals (-), hydrocarbons (MESH:D006838)
- **Species:** Bacteria Latreille et al. 1825 (Bacteria stick insect, genus) [taxon 629395], Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12895013/full.md

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Source: https://tomesphere.com/paper/PMC12895013