# Recurrent intussusception associated with pneumatosis cystoides coli: A pediatric case report

**Authors:** Sarah Barrett, Tanyaporn Kaenkumchorn, Pooja Thakrar, Rosellen Choi, Rose Lee

PMC · DOI: 10.1002/jpr3.70109 · JPGN Reports · 2025-11-14

## TL;DR

A 7-year-old girl with recurring intussusception was found to have PCC, which resolved completely after hyperbaric oxygen treatment.

## Contribution

This case report highlights the successful use of hyperbaric oxygen therapy in treating PCC-related intussusception in a pediatric patient.

## Key findings

- PCC was identified as the cause of recurrent intussusception in a child.
- Hyperbaric oxygen treatment led to complete resolution of PCC.
- Conventional treatments like metronidazole and dietary changes did not resolve PCC.

## Abstract

Pneumatosis cystoides coli (PCC) describes gas‐filled cysts within the wall of the gastrointestinal tract and is uncommon in children. We report a 7‐year‐old female with a history of recurrent ileocolic intussusception secondary to PCC. Her initial episodes of intussusception resolved spontaneously or with air enema, but no lead point was identified. On her third presentation to the emergency department with a similar complaint, computed tomography of the abdomen and pelvis revealed extensive colonic mural air‐filled cystic lesions which had been present during prior episodes of intussusception. The patient was treated with metronidazole, a sorbitol‐free diet, and continuous low‐flow oxygen. Despite these treatments, PCC persisted on imaging. Hyperbaric oxygen treatment was initiated, leading to complete resolution of PCC without any further episodes.

## Linked entities

- **Chemicals:** metronidazole (PubChem CID 4173), sorbitol (PubChem CID 5780)
- **Diseases:** intussusception (MONDO:0007835)

## Full-text entities

- **Diseases:** PCC (MESH:D011006), intussusception (MESH:D007443)
- **Chemicals:** oxygen (MESH:D010100), metronidazole (MESH:D008795), sorbitol (MESH:D013012)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12894068/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12894068/full.md

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Source: https://tomesphere.com/paper/PMC12894068