# Vitamin B12 deficiency in a pediatric patient with gastric obstruction and jejunal feeding dependence: A case report

**Authors:** Angela H. Nguyen, Dorsey Bass, Rachel E. Herdes

PMC · DOI: 10.1002/jpr3.70117 · JPGN Reports · 2025-12-09

## TL;DR

A child with a complex gastrointestinal condition and B12 deficiency improved quickly with high-dose enteral B12 supplementation.

## Contribution

Highlights a rare case of B12 deficiency in a pediatric patient with jejunal feeding dependence and unusual anatomy.

## Key findings

- High-dose enteral B12 resolved neuromuscular symptoms in a pediatric patient.
- B12 deficiency occurred despite jejunal feeding, indicating absorption challenges.
- The case emphasizes the need to monitor nutritional deficiencies in patients with complex GI anatomy.

## Abstract

Pediatric B12 deficiency is most caused by insufficient dietary intake, malabsorption or autoimmune gastritis. We present a unique case of B12 deficiency in a pediatric patient with complex gastrointestinal anatomy and jejunal nutritional dependence nearly two decades after unsuccessful surgical intervention. High‐dose enteral B12 supplementation via jejunostomy tube resulted in rapid resolution of the patient's neuromuscular manifestations of vitamin B12 deficiency, highlighting the importance of considering nutritional deficiencies in patients reliant on jejunal enteral nutrition and anatomic differences.

## Linked entities

- **Chemicals:** vitamin B12 (PubChem CID 73415824)

## Full-text entities

- **Diseases:** gastric obstruction (MESH:D017219), malabsorption (MESH:D008286), nutritional deficiencies (MESH:D044342), autoimmune gastritis (MESH:D005756), B12 deficiency (MESH:D014806)
- **Chemicals:** B12 (MESH:C034730)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12894065/full.md

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Source: https://tomesphere.com/paper/PMC12894065