# Bullous Pemphigoid in Children: Sustained 8‐Year Remission After Short‐Course Corticosteroid Therapy

**Authors:** Fengchang Wang, Hongxia Li, Yue Xu, Wenge Wang

PMC · DOI: 10.1002/ccr3.71882 · Clinical Case Reports · 2026-02-11

## TL;DR

A 5-year-old child with bullous pemphigoid achieved 8 years of remission after a short corticosteroid treatment, offering insights into managing this rare skin condition in children.

## Contribution

The paper presents a rare long-term case of childhood bullous pemphigoid successfully treated with a short corticosteroid course.

## Key findings

- The child's skin lesions resolved within 2 weeks of corticosteroid treatment.
- No recurrence or complications were observed during an 8-year follow-up.
- Short-course corticosteroids may be effective for childhood bullous pemphigoid.

## Abstract

This article reports a case of bullous pemphigoid (BP) in a 5‐year‐old child who achieved sustained remission for up to 8 years following short‐course systemic corticosteroid therapy, aiming to provide observational evidence for the clinical management of childhood BP. The child initially presented with pruritic rashes and blisters, which were once misdiagnosed as infectious rashes; finally, the diagnosis was confirmed by direct immunofluorescence (DIF), histopathology, and other examinations. After treatment with systemic glucocorticoids combined with anti‐infective therapy, the skin lesions basically resolved within 2 weeks, and the tapering and discontinuation of drugs were completed within 26 weeks of treatment. During the 8‐year follow‐up period, no recurrence or treatment‐related complications were observed. This case suggests that although childhood BP is prone to misdiagnosis, it responds well to glucocorticoid treatment, and long‐term remission can be achieved with a relatively short treatment course; however, this model still needs to be verified by large‐sample studies.

This article reports a case of childhood bullous pemphigoid (BP) with an 8‐year long‐term follow‐up. Although the patient was initially misdiagnosed, she exhibited a favorable response to systemic corticosteroid treatment. After receiving treatment, the child achieved sustained remission and remained recurrence‐free for 8 years.

## Linked entities

- **Diseases:** bullous pemphigoid (MONDO:0019082)

## Full-text entities

- **Diseases:** infective (MESH:D007239), blisters (MESH:D001768), BP (MESH:D010391), skin lesions (MESH:D012871), infectious rashes (MESH:D005076)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12893868/full.md

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Source: https://tomesphere.com/paper/PMC12893868