# Generating cerebellar organoids from pluripotent stem cells

## TL;DR

This paper reviews methods for creating cerebellar organoids and suggests standards to improve their reliability and usefulness in research.

## Contribution

The paper introduces suggested quality control standards and biological readouts for cerebellar organoid research.

## Key findings

- Current approaches to generate cerebellar organoids are summarized.
- Common quality control standards are proposed for this emerging area.
- Applications of cerebellar organoids in modeling development and disease are highlighted.

## Abstract

Cerebellar organoids present promising tools for the modelling of human cerebellar development and diseases. As this young field grows, robust standards and transparent reporting practices are needed to ensure the reproducibility and utility of the generated cerebellar organoid models. Here, we summarize current approaches to generate cerebellar organoids and their applications. We suggest common quality control standards and biological readouts that should be considered in this emerging area.

Summary: This Special Article provides a comprehensive overview of the methods, applications and considerations for the generation of cerebellar organoids.