# Longevity and Innovation: Cardiac Resynchronization Therapy in a 100‐Year‐Old Patient With Severe Heart Failure—A 4‐Year Follow‐Up

**Authors:** Ayman Helal, Ibrahim Antoun, Rachana Prasad

PMC · DOI: 10.1155/cric/7961581 · 2026-02-11

## TL;DR

A 100-year-old man with severe heart failure showed significant improvement after receiving cardiac resynchronization therapy, maintaining quality of life for four years.

## Contribution

Demonstrates the successful use of CRT-P in a very elderly patient with severe heart failure, challenging age-based treatment hesitations.

## Key findings

- CRT-P implantation led to significant symptomatic improvement in a 100-year-old patient.
- The patient maintained functional independence for four years post-implantation.
- CRT-P can be a viable treatment option for very elderly patients with heart failure.

## Abstract

Cardiac resynchronization therapy (CRT) has been shown to improve outcomes in patients with severe left ventricular systolic dysfunction (LVSD) and electrical dyssynchrony. This case report presents a 100‐year‐old male with a history of atrial fibrillation (AF), left bundle branch block (LBBB), and ischemic heart disease, who was admitted with chest pain and episodes of bradycardia. After careful consideration, CRT‐P was successfully implanted. The patient′s condition was closely monitored postimplantation, and a 4‐year follow‐up revealed significant symptomatic improvement and functional independence. This report highlights the importance of CRT‐P in improving quality of life and managing heart failure in very elderly patients.

## Linked entities

- **Diseases:** atrial fibrillation (MONDO:0004981), ischemic heart disease (MONDO:0024644), heart failure (MONDO:0005252)

## Full-text entities

- **Diseases:** LVSD (MESH:D018487), Heart Failure (MESH:D006333), chest pain (MESH:D002637), electrical dyssynchrony (MESH:D004556), AF (MESH:D001281), LBBB (MESH:D002037), ischemic heart disease (MESH:D017202), bradycardia (MESH:D001919)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12892197/full.md

---
Source: https://tomesphere.com/paper/PMC12892197