# Menstrual Cycle Dynamics and Their Impact on Psychotherapy: Insights From a Mixed‐Methods Study

**Authors:** Marie Anderlik, Jasmina Eifert, Manuela Gander, Anna Buchheim, Alexander Karabatsiakis

PMC · DOI: 10.1002/cpp.70237 · 2026-02-10

## TL;DR

This study explores how menstrual cycle phases affect women's experiences in psychotherapy, showing that therapy satisfaction and symptoms vary across the cycle.

## Contribution

The study introduces the idea that integrating menstrual cycle dynamics into psychotherapy can improve personalized treatment outcomes for women.

## Key findings

- Participants reported lower therapy satisfaction during premenstrual and perimenstrual phases.
- Symptoms worsened during these phases, affecting emotional states and therapy effectiveness.
- Open discussion of the menstrual cycle in therapy improved treatment outcomes for participants.

## Abstract

Despite substantial research on the physiological and psychological effects of the menstrual cycle (MC) on somatic and mental health, its impact on psychotherapy remains largely overlooked. Importantly, MC follows a recurring pattern of inflammatory activity. Emotional states, mood, cognitive functioning and sleep patterns fluctuate across the MC, affecting overall functioning and well‐being. Additionally, hormonal shifts across the cycle are linked to the exacerbation of psychiatric symptoms, particularly in premenopausal women who exhibit heightened sensitivity to normal changes in sex steroid levels. However, MC‐related hormonal fluctuations and inflammatory processes are rarely considered in psychotherapeutic settings. This exploratory mixed‐methods study examined how MC‐related fluctuations influence clients' psychotherapy experiences. In an online survey setting, a total of N = 425 female clients completed the Client Satisfaction Questionnaire‐8 (CSQ‐8) and the WHO Well‐Being Index (WHO‐5), alongside qualitative questions on symptom and therapy experiences. Most participants received cognitive‐behavioural (35.5%), psychodynamic (14.4%), systemic (9.4%) or humanistic (6.8%) therapy, while 33.9% were unsure of their therapy orientation, mostly in outpatient settings. Quantitative findings revealed reduced therapy satisfaction during premenstrual and perimenstrual phases compared with other phases. Qualitative data highlighted symptom exacerbation during these phases, negatively affecting emotional states, therapeutic participation, cognitive functioning and perceptions of therapy's necessity and effectiveness. Participants reported that the open discussion of the MC in therapy improved treatment outcomes. They advocated for individualized consideration of MC‐related factors in therapy planning. These findings underscore the need for more personalized clinical approaches that integrate MC‐related dynamics into psychotherapy to optimize treatment outcomes.

Psychotherapists should be aware that clients' emotional states, cognitive functioning and therapy satisfaction fluctuate across menstrual cycle phases.Premenstrual and perimenstrual phases are associated with lower therapy satisfaction and heightened symptom severity.Integrating menstrual cycle awareness into case formulation and therapy planning supports more personalized, phase‐sensitive interventions.Considering menstrual cycle dynamics in psychotherapy may offer clinically relevant insights and inform more personalized approaches to women's mental healthcare.

Psychotherapists should be aware that clients' emotional states, cognitive functioning and therapy satisfaction fluctuate across menstrual cycle phases.

Premenstrual and perimenstrual phases are associated with lower therapy satisfaction and heightened symptom severity.

Integrating menstrual cycle awareness into case formulation and therapy planning supports more personalized, phase‐sensitive interventions.

Considering menstrual cycle dynamics in psychotherapy may offer clinically relevant insights and inform more personalized approaches to women's mental healthcare.

## Full-text entities

- **Diseases:** inflammatory (MESH:D007249), psychiatric (MESH:D001523)
- **Chemicals:** steroid (MESH:D013256)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12891931/full.md

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Source: https://tomesphere.com/paper/PMC12891931