# Pseudomyogenic Hemangioendothelioma of the Femur Treated by Intercalary Resection and Massive Allograft Reconstruction: A Case Report

**Authors:** Fernando N. Martín Cocilova, Elisabetta Neri, Filippo Nozzoli, Tiziana Tatti, Annarita Palomba, Giuliana Roselli, Domenico A. Campanacci

PMC · DOI: 10.1155/cro/2427724 · 2026-02-10

## TL;DR

A rare tumor in the femur was successfully treated with bone removal and graft reconstruction, resulting in full recovery.

## Contribution

Reports a successful treatment of primary intraosseous PHME using intercalary resection and allograft reconstruction.

## Key findings

- The patient remained disease-free after more than 2 years of follow-up.
- Radiographic evidence showed successful allograft union and full weight-bearing capability.

## Abstract

Pseudomyogenic hemangioendothelioma (PHME) is a very rare vascular tumor that usually arises in the extremities, mainly cutaneous or subcutaneous, but also occurs in deeper locations, such as muscles and bone. Less than 200 cases have been reported so far, and primary intraosseous PHMEs are further infrequent. We present a clinical case of PMHE of the femur in a young male adult successfully treated by intercalary resection and massive allograft reconstruction with plates fixation. After more than 2 years of follow‐up, the patient is disease‐free and asymptomatic, walking with full weight‐bearing with radiographic evidence of allograft union.

## Linked entities

- **Diseases:** Pseudomyogenic hemangioendothelioma (MONDO:0975754)

## Full-text entities

- **Diseases:** PHME (MESH:D006390), vascular tumor (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

11 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12891804/full.md

---
Source: https://tomesphere.com/paper/PMC12891804