# Ischemic Stroke in a Talapoin Monkey ( Miopithecus talapoin )

**Authors:** Lucas dos Reis de Souza, Virginia Beatriz D’assunção Castro, Daniel Oliveira Santos, Nayara Ferreira de Paula, Paula Cristina Senra Lima, Rafael Otavio Cançado Motta, Carlyle Mendes Coelho, Herlandes Penha Tinoco, Rodrigo Otavio Silveira Silva, Renato Lima Santos, Ayisa Rodrigues de Oliveira

PMC · DOI: 10.1111/jmp.70064 · 2026-02-02

## TL;DR

An old talapoin monkey died from sudden neurological symptoms caused by an ischemic stroke, as confirmed by post-mortem examination.

## Contribution

This case report documents ischemic stroke in a talapoin monkey, a rare occurrence in non-human primates.

## Key findings

- The monkey showed sudden neurological signs and died within 24 hours.
- Necropsy found a large brain infarct with thrombus and neuronal damage.
- Arteriosclerosis was identified as a contributing factor to the stroke.

## Abstract

A captive senile talapoin monkey (
Miopithecus talapoin
) developed sudden neurological signs and died within 24 h. Necropsy revealed an extensive infarct in the right hemisphere, from occipital to frontal lobe. Microscopy showed a thrombus, neuronal edema, and necrosis, and arteriosclerosis, characterizing an ischemic stroke.

## Linked entities

- **Diseases:** ischemic stroke (MONDO:1060198)
- **Species:** Miopithecus talapoin (taxon 36231)

## Full-text entities

- **Diseases:** thrombus (MESH:D013927), infarct (MESH:D007238), Ischemic Stroke (MESH:D002544), arteriosclerosis (MESH:D001161), necrosis (MESH:D009336), edema (MESH:D004487)
- **Species:** Miopithecus talapoin (talapoin, species) [taxon 36231]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12891754/full.md

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Source: https://tomesphere.com/paper/PMC12891754