# Work productivity, associated risk factors and costs on presenteeism and absenteeism in Chinese patients with young‐onset type‐2 diabetes in Hong Kong

**Authors:** Juliana N. M. Lui, Kelly T. C. Wong, Eric S. H. Lau, Sunny C. S. Chan, Nga Sze Wong, Jenny Y. Z. Zhang, Kit Ming Wai, Chun Kwan O, Baoqi Fan, Hongjiang Wu, Ronald C. W. Ma, Alice P. S. Kong, Andrea O. Y. Luk, Elaine Y. K. Chow, Juliana C. N. Chan

PMC · DOI: 10.1111/dom.70352 · Diabetes, Obesity & Metabolism · 2025-12-16

## TL;DR

This study examines work productivity and related costs in Chinese patients with young-onset type-2 diabetes in Hong Kong, revealing significant economic impacts.

## Contribution

The study is the first to quantify productivity losses specifically in Chinese patients with young-onset type-2 diabetes.

## Key findings

- Chinese patients with young-onset type-2 diabetes reported significant productivity loss, with a mean presenteeism score of 7.34/10.
- Annual productivity losses in Hong Kong are estimated at US$444 million, with presenteeism accounting for most of the cost.
- Factors like albuminuria and use of lipid-lowering medications were linked to reduced productivity.

## Abstract

Those with young‐onset type‐2 diabetes (YOD), diagnosed before age of 40 years, experience heightened risk of complications. The economic burden extends beyond medical costs, impacting work productivity.

Chinese patients with YOD were recruited between June 2023 and April 2024 in the Precision Medicine to redefine Insulin Secretion and Monogenic diabetes Trial in Hong Kong (NCT04049149). Presenteeism and absenteeism were measured using the World Health Organization Health and Performance Questionnaire.

Of the 639 invited participants, 603 (94%) completed the questionnaire, with 444 employed participants with type‐2 diabetes (40.1% female, 80.4% 40–50 years, 32.9% 5–10 years with diabetes, 53.3% hemoglobin A1c (HbA1c) <7.0%, 75.2% low‐density lipoprotein cholesterol <2.6 mmol/L, 42.3% body mass index ≥25 < 30 kg/m2). Participants reported mean presenteeism score of 7.34/10, 93.9% experiencing productivity loss with 0.48 mean sick days. Increased productivity was associated with females, child care, flexible work schedules and higher salary. Reduced productivity was related to, albuminuria, use of lipid‐lowering medications and more sick leaves. With approximately 38 700 patients with YOD in Hong Kong, territory‐wide productivity losses are projected to reach US$444 million annually (presenteeism: US$419 million, absenteeism: US$25 million).

This study is the first to quantify productivity costs in Chinese patients with YOD, highlighting the need for work place policies, intensive treatment and management strategies to enhance support for individuals with YOD.

## Linked entities

- **Diseases:** type-2 diabetes (MONDO:0005148)

## Full-text entities

- **Genes:** INS (insulin) [NCBI Gene 3630] {aka IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10}
- **Diseases:** albuminuria (MESH:D000419), type-2 diabetes (MESH:D003924), Monogenic diabetes (MESH:D003920), YOD (MESH:C564219)
- **Chemicals:** lipid-lowering medications (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

54 references — full list in the complete paper: https://tomesphere.com/paper/PMC12890741/full.md

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Source: https://tomesphere.com/paper/PMC12890741