# The emerging role of echocardiography-based techniques in cardio-onco-hematology

**Authors:** Yichan Zhang, Mingxing Xie, Jing Wang, Bo Zhang

PMC · DOI: 10.3389/fonc.2026.1696096 · Frontiers in Oncology · 2026-01-28

## TL;DR

This paper reviews how echocardiography techniques help detect early heart damage in cancer patients, especially those with blood cancers.

## Contribution

The paper highlights the role of echocardiography-based techniques in early detection and management of cardiac dysfunction in hematological malignancy patients.

## Key findings

- Echocardiography-based techniques can detect subclinical myocardial damage in cancer patients.
- Early detection allows for timely cardioprotective interventions.
- Techniques like speckle tracking and stress echocardiography assess myocardial function effectively.

## Abstract

In decades, the overall survival rate for cancer patients has improved significantly with continuous advances in cancer treatment technologies. However, cancer therapeutics-related cardiac dysfunction (CTRCD) has been one of the most worrying side effects, particularly in patients with hematological malignancies (HM), affecting the quality of life for cancer survivors. Early detection and prompt treatment are of vital importance. Echocardiography-based techniques can even identify subclinical myocardial damages, which is crucial for preventing irreversible myocardial damage. Conventional transthoracic echocardiography, speckle tracking imaging, myocardial work and stress echocardiography can assess myocardial global and segmental systolic function in multiple aspects. A significant decline of those parameters indicates that cardioprotective therapy should be initiated with close monitoring. This review will discuss the diagnosis and prognostic role of echocardiography-based techniques in patients with HM.

## Full-text entities

- **Diseases:** myocardial damage (MESH:D009202), CTRCD (MESH:D006338), cardiac dysfunction (MESH:D006331), HM (MESH:D019337), cancer (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

91 references — full list in the complete paper: https://tomesphere.com/paper/PMC12890683/full.md

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Source: https://tomesphere.com/paper/PMC12890683