# Integrating Behavioral Science-Based Interventions in the Treatment of Refractory Atopic Dermatitis and Associated Behavioral Problems

**Authors:** Marei Omori, Tomoki Yaguchi, Chisato Jimbo, Kouhei Hagino, Daisuke Harama, Daichi Suzuki, Kotaro Umezawa, Fumi Ishikawa, Seiko Hirai, Kenji Toyokuni, Tatsuki Fukuie, Yukihiro Ohya, Kiwako Yamamoto-Hanada

PMC · DOI: 10.31662/jmaj.2025-0070 · JMA Journal · 2025-11-21

## TL;DR

A child with severe eczema and behavioral issues improved significantly after combining medical treatment with behavioral science-based interventions.

## Contribution

Demonstrates the effectiveness of integrating behavioral science interventions in treating refractory atopic dermatitis and associated behavioral problems.

## Key findings

- Behavioral interventions led to resolution of tantrums and scratching behaviors in an 8-year-old with AD.
- Combining medical and behavioral approaches resulted in long-term eczema remission and improved behavior post-discharge.
- The case highlights the importance of addressing both physical and behavioral aspects of AD in treatment.

## Abstract

This report highlights the successful integration of behavioral science-based interventions in the treatment of an 8-year-old girl with atopic dermatitis (AD) and behavioral problems, including tantrums. The patient, who had a history of poorly managed AD, presented with worsened eczema and sleep disturbances, in addition to increased tantrums, scratching, and reluctance to attend school. She was admitted for inpatient treatment, which included standard AD management and multidisciplinary care, focusing on proper skin care, diet, and lifestyle changes. Despite relief of her eczema, her problematic behaviors persisted, which worsened her condition.

To address this, behavioral interventions were implemented. Anger management techniques were introduced, whereby the patient assessed her anger levels and used relaxation methods. She was taught alternative behaviors to manage the itching, such as applying topical treatments or interacting with her favorite stuffed animal. Her parents also received guidance on managing her behavior. Over her three-month hospitalization, her tantrums and problematic behaviors resolved, and her AD went into remission. Post-discharge, her eczema remained well controlled, and her behavior improved, with no recurrence of tantrums or other issues.

This case illustrates the importance of combining pharmacological treatments with behavioral interventions in managing AD and associated psychosocial challenges. Behavioral science-based approaches can play a crucial role in alleviating behavioral issues linked to AD, such as anger and scratching, which can further exacerbate the condition. In this case, behavioral therapy effectively alleviated the patient’s behavior problems and improved eczema control, underscoring the need for clinicians to be equipped to address both the physical and behavioral aspects of AD.

## Linked entities

- **Diseases:** atopic dermatitis (MONDO:0004980), eczema (MONDO:0004980)

## Full-text entities

- **Diseases:** Behavioral Problems (MESH:D001523), sleep disturbances (MESH:D012893), eczema (MESH:D004485), AD (MESH:D003876), itching (MESH:D011537)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC12889884/full.md

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Source: https://tomesphere.com/paper/PMC12889884