# Crisis Management of Emerging/Re-Emerging Infectious Diseases in People with HIV in Japan

**Authors:** Eisuke Adachi, Hiroshi Yotsuyanagi, Tomoya Saito

PMC · DOI: 10.31662/jmaj.2025-0433 · JMA Journal · 2025-12-12

## TL;DR

The paper discusses how marginalized groups like people with HIV in Japan face unique challenges during infectious disease outbreaks, based on experiences from a Tokyo hospital during the COVID-19 and mpox outbreaks.

## Contribution

The study provides insights into the specific vulnerabilities of people with HIV during emerging infectious disease crises in Japan.

## Key findings

- People with HIV experienced vaccine non-responsiveness and prolonged infections during the COVID-19 pandemic.
- The mpox outbreak highlighted population-specific complications influenced by social and epidemiological factors.
- Delayed detection and spread in marginalized communities can deepen health disparities.

## Abstract

Emerging and re-emerging infectious diseases have disproportionately affected marginalized groups such as people with HIV (PWH), yet their specific needs are often overlooked. Drawing on the experience of IMSUT Hospital in Minato ward, central Tokyo―a district that includes Roppongi and Ginza, and serves as a referral center for HIV care―during the COVID-19 pandemic, we highlight how structural factors, stigma, and delayed access to care shaped the impact on PWH. While general medical responses evolved rapidly, HIV-specific vulnerabilities such as vaccine non-responsiveness and prolonged infection persisted. The subsequent mpox outbreak in Tokyo, affecting many PWH, further illustrated how emerging infections in marginalized communities can present with population-specific complications influenced by social and epidemiological contexts. Without such measures, outbreaks among PWH and other vulnerable groups may remain undetected for longer periods and spread more widely, thereby deepening existing disparities.

## Linked entities

- **Diseases:** COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** COVID-19 (MESH:D000086382), Infectious Diseases (MESH:D003141), HIV (MESH:D015658), infection (MESH:D007239)
- **Species:** Homo sapiens (human, species) [taxon 9606], Human immunodeficiency virus 1 (no rank) [taxon 11676]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12889363/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12889363/full.md

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Source: https://tomesphere.com/paper/PMC12889363