# An Unusually Large Oral Lipoma of Buccal Mucosa and Vestibulum: A Case Report

**Authors:** Petra Stazić, Mislav Ušljebrka, Ante Mihovilović, Ante Pojatina, Andrija Radoš, Jure Martinić, Daniel Jerković

PMC · DOI: 10.1155/crid/3913290 · Case Reports in Dentistry · 2026-02-10

## TL;DR

This case report describes a rare, large lipoma in the mouth that was successfully surgically removed without complications.

## Contribution

The novelty lies in presenting an unusually large lipoma in the buccal mucosa and vestibule with a long growth history and successful surgical management.

## Key findings

- The lipoma was located in the buccal mucosa and vestibule and had been growing for 8 years.
- Surgical excision was performed under local anesthesia with no recurrence or nerve damage observed at 3 months.
- The case highlights the importance of differential diagnosis and careful surgical planning for lipomas in sensitive oral regions.

## Abstract

Lipoma is a benign tumor of fatty tissue. Although lipomas are common tumors of mesenchymal origin in the human body, they rarely occur in the oral and maxillofacial region with a prevalence of 1%–4%. Even though lipomas in the oral cavity can appear anywhere, their etiology remains unclear. These tumors grow slowly and are painless, soft, and often encapsulated. Nevertheless, this tumor, with its growth, can cause speech, chewing, and denture fabrication difficulties and can be associated with pain, swelling, and numbness. Since it can be differentially diagnosed with liposarcoma, the preferred treatment for this tumor is adequate surgical excision, which is associated with a low recurrence rate. This report presents the clinical case of a large oral lipoma located in buccal mucosa and vestibule of the oral cavity that has been growing for the past 8 years. Surgical excision of the lipoma was performed under local anesthesia, requiring precise dissection due to its proximity to the mental nerve to minimize potential nerve damage. At the 3‐month follow‐up examination, the clinical findings were normal, with no signs of recurrence and no paresthesia in the operated area.

## Linked entities

- **Diseases:** lipoma (MONDO:0005106), liposarcoma (MONDO:0003585)

## Full-text entities

- **Diseases:** nerve damage (MESH:D000080902), pain (MESH:D010146), paresthesia (MESH:D010292), numbness (MESH:D006987), swelling (MESH:D004487), Mucosa (MESH:D018442), tumor (MESH:D009369), liposarcoma (MESH:D008080), oral (MESH:D020820), Lipoma (MESH:D008067)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12888973/full.md

## References

28 references — full list in the complete paper: https://tomesphere.com/paper/PMC12888973/full.md

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Source: https://tomesphere.com/paper/PMC12888973