# The current consensus on ulcerative colitis, and the evidence and perspectives on the influence of gut microbiota on it

## TL;DR

This paper reviews ulcerative colitis, focusing on how gut microbiota influences the disease and treatment options.

## Contribution

The paper provides a comprehensive review of gut microbiota's role in ulcerative colitis and its therapeutic implications.

## Key findings

- Gut microbiome disruption is closely linked to ulcerative colitis.
- Intestinal flora may serve as a key measure for clinical judgment in UC.
- Microbiota-targeted therapies could offer new treatment strategies.

## Abstract

Ulcerative colitis (UC) is a chronic non-specific inflammatory disease, the pathogenesis is not clear, there is no clinical cure. The number of cases of UC has increased worldwide in recent years due to industrialization and social pressures. At present, the therapeutic effectiveness of UC remains controversial. Although researchers have conducted certain studies on the pathogenesis of UC, its pathogenesis and anti-UC pathogenesis have not been fully revealed. Previous studies have found a close relationship between human gut microbes and UC, and may be the most important measure of UC for clinical judgment. Many studies have linked UC to disruption of the gut microbiome, which is one of the most important features of UC. This paper reviews the clinical characteristics, pathogenesis and current treatment strategies of UC, and reviews the interaction between intestinal flora and UC as well as the therapeutic effects of intestinal flora, providing reference for the prevention and treatment of UC.