# Injectables and Facelifts: Can We Coexist? A Retrospective Chart Review Assessing Injectable Treatments Preceding and Following Rhytidectomy

**Authors:** Bridget Myers, Maya Firsowicz, Payvand Kamrani, Steven Dayan, Sabrina Fabi

PMC · DOI: 10.1111/jocd.70690 · Journal of Cosmetic Dermatology · 2026-02-09

## TL;DR

This study explores how injectable treatments and facelift surgery can be used together safely, finding no significant complications from combining them.

## Contribution

The study provides early evidence that injectables before or after facelifts do not increase surgical risks in a small patient cohort.

## Key findings

- All patients used neurotoxin before facelifts, with no significant complications reported.
- 60% of patients resumed filler treatments post-surgery, and satisfaction with facelift outcomes was high.
- The study suggests injectables and facelifts can coexist safely, but larger studies are needed for confirmation.

## Abstract

Facelift surgery is a cornerstone of facial rejuvenation, yet it may not fully address volume loss, skin quality, or other age‐related changes. Minimally invasive procedures—such as injectables and energy‐based devices—are increasingly utilized before and after facelift surgery, though their impact on surgical outcomes remains uncertain.

The objective of this single‐center retrospective pilot study is to describe patterns of minimally invasive procedures among patients undergoing facelift surgery in a real‐world clinical setting and identify areas for future investigations regarding their potential influence on surgical outcomes.

We analyzed data from 20 patients who underwent facelift surgery and had a documented history of neurotoxin, filler, biostimulator, or energy‐based device treatment. Data included patient demographics, treatment history, surgical details, and post‐operative satisfaction. Given the limited sample size and retrospective design, the analyses done were descriptive and exploratory in nature.

All patients received neurotoxin prior to facelift, 90% received hyaluronic‐acid filler, and 55% received poly‐L‐lactic acid or calcium hydroxylapatite. Following surgery, all patients resumed neurotoxin use, and 60% received filler treatments within the first post‐operative year. No reported significant surgical complications occurred because of prior filler or biostimulator treatments, and patient satisfaction was high for facelift outcomes.

Within our small, retrospective cohort, prior injectable or energy‐based device use was not associated with an increased risk of observable adverse surgical outcomes; however, the limited sample size precludes definitive assessment of safety or risk. Larger, prospectively designed studies are warranted to validate these early observations and optimally define best practices for combining surgical and nonsurgical rejuvenation.

## Linked entities

- **Chemicals:** calcium hydroxylapatite (PubChem CID 14781)

## Full-text entities

- **Diseases:** volume loss (MESH:D016388)
- **Chemicals:** hyaluronic-acid (MESH:D006820), poly-L-lactic acid (MESH:C033616), calcium hydroxylapatite (MESH:D017886)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC12887548/full.md

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Source: https://tomesphere.com/paper/PMC12887548