# Pan beriberi in a Young Male: A Case Report

**Authors:** Sonam Yangzom, Dechen Wangmo, Diki Dolkar, Kezang Tshomo, Dechen Pelden, Tenzin Kelzang

PMC · DOI: 10.1002/ccr3.72033 · Clinical Case Reports · 2026-02-09

## TL;DR

A young man with unexplained heart failure, neurological issues, and gut problems was diagnosed with pan beriberi, a severe thiamine deficiency that can be treated with high-dose thiamine.

## Contribution

Highlights the importance of considering pan beriberi in young patients with acute heart failure and neurological symptoms.

## Key findings

- Pan beriberi can present with acute heart failure, neurological deficits, and gastrointestinal pseudo-obstruction in young patients.
- High-dose thiamine therapy can be lifesaving even without laboratory confirmation.
- Chest X-rays showed reversible cardiac involvement due to thiamine deficiency.

## Abstract

Pan beriberi should be considered in young patients with unexplained acute heart failure, neurological deficits, and gastrointestinal pseudo‐obstruction, particularly in malnutrition or chronic alcohol use. Early clinical recognition and prompt high dose thiamine therapy can be lifesaving, even where laboratory confirmation is unavailable.

Chest X‐ray findings of cardiomegaly and pulmonary congestion in pan beriberi reflecting reversible cardiac involvement due to thiamine deficiency.

## Linked entities

- **Chemicals:** thiamine (PubChem CID 1130)
- **Diseases:** heart failure (MONDO:0005252)

## Full-text entities

- **Diseases:** Pan beriberi (MESH:D001602), gastrointestinal pseudo-obstruction (MESH:D007418), neurological deficits (MESH:D009461), heart failure (MESH:D006333), malnutrition (MESH:D044342)
- **Chemicals:** thiamine (MESH:D013831), alcohol (MESH:D000438)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12885931/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12885931/full.md

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Source: https://tomesphere.com/paper/PMC12885931