# Bio‐Inspired Micro‐Fin‐Assisted Multi‐Modal Vascular Intervention

**Authors:** Xu Liu, Qiang Luo, Zhuoqun Cao, Hongde Li, Xi Chen, Hong Wang, Mao Chen, Ziyu Ren, Wenqi Hu

PMC · DOI: 10.1002/advs.202515119 · Advanced Science · 2025-11-27

## TL;DR

A new magnetic guidewire with micro-fins improves navigation in complex blood vessels, making procedures faster and more efficient.

## Contribution

A magnetic guidewire with micro-fins is introduced to enhance vascular navigation through fluid drag and torque augmentation.

## Key findings

- The micro-fins allow traversal of bifurcations at 15 mT magnetic field strength, compared to 34 mT in conventional designs.
- The device tolerates magnetic field misalignments up to 45 degrees and enables bidirectional crawling and self-correction.
- In vivo tests showed a 50% reduction in procedure time compared to commercial guidewires.

## Abstract

Interventional procedures are essential in vascular medicine, but precise navigation through tortuous vasculature remains difficult due to the limited steerability of guidewires in complex anatomical regions. Magnetic guidewires have been developed to address this limitation, yet they typically depend on accurate field control using robotic‐arm‐mounted magnets or electromagnets, which constrains their use in space‐limited intervention room. Here, a magnetic guidewire with a micro‐fin‐integrated tip for multimodal vascular intervention is introduced. The micro‐fins respond to external magnetic fields and generate additional torques through fluid drag and vessel wall contact forces, supplementing the magnetic torque and gradient forces of conventional designs. This combination enables the guidewire to pass bifurcations under lower magnetic field strength, reduced from 34 to 15 mT in the trials, and to tolerate external field misalignments up to 45 degrees. The micro‐fin structure also permits bidirectional crawling and self‐correction from buckling. In vivo testing in rabbit vascular models shows the device reduced time by ≈50% compared to a commercial guidewire, even when the magnetic field is manually applied, and allows full access to major arteries within 1 min. These findings demonstrate that micro‐fins integration provides advantages that improve the control and efficiency of magnetic guidewires in complex vascular environments.

A magnetic guidewire with a micro‐fin–integrated tip is introduced for multimodal cardiovascular navigation. The micro‐fins exploit fluid drag to augment magnetic torque, enabling bifurcation traversal at 15 mT, tolerating 45° misalignment, bidirectional crawling, and buckle self‐correction. During in vivo tests in rabbit models, procedures are ≈50% faster than using a commercial guidewire, enabling arterial access within a minute.

## Full-text entities

- **Species:** Oryctolagus cuniculus (domestic rabbit, species) [taxon 9986]

## Full text

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## Figures

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## References

57 references — full list in the complete paper: https://tomesphere.com/paper/PMC12884816/full.md

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Source: https://tomesphere.com/paper/PMC12884816