# Early experience with pericardiectomy for constrictive pericarditis in Ile-Ife, Nigeria: a retrospective analysis

**Authors:** Olugbenga O Ojo, Uvie U Onakpoya, Oluwaseun R Akanbi, Abayomi E Oguns, Mathias O Ikokoh

PMC · DOI: 10.4314/ahs.v25i4.17 · African Health Sciences · 2025-12-01

## TL;DR

This paper reports on pericardiectomy outcomes in Nigeria, showing most patients improved after surgery for constrictive pericarditis.

## Contribution

The study provides early experience and outcomes of pericardiectomy in a Nigerian tertiary hospital setting.

## Key findings

- Thirteen patients underwent pericardiectomy with a median ICU stay of 2 days and 1 mortality.
- Over 90% of surviving patients showed significant improvement in heart function at 12 months.
- Common symptoms included dyspnea and ascites, with most patients in advanced NYHA classes pre-surgery.

## Abstract

Constrictive pericarditis is a rare but important cause of diastolic heart failure. Its uniqueness lies in the fact that surgery (pericardiectomy) remains the mainstay of treatment. Globally, the leading causes of constrictive pericarditis include idiopathic, mediastinal irradiation, post cardiac surgery and tuberculosis.

Patients who underwent pericardiectomy at our tertiary hospital between January 2019 and December 2024 were retrospectively studied with the aim of discussing our experience with the procedure and its outcomes. Data including baseline demographics, preoperative conditions, intraoperative details, and postoperative outcomes were collected from clinical records and analysed.

Thirteen patients had total pericardiectomy during the period under review. The median age was 28 years with dyspnoea and ascites being the most common symptoms. Most patients (61.6%) presented in NYHA class III and IV and were above ASA II classification at the time of surgery. Pericardiectomy was done via median sternotomy and without cardiopulmonary bypass in all cases, with an average surgery duration of 284.5 mins. Postoperative complications included low cardiac output, acute kidney injury, coagulopathy, and prolonged pleural effusion. Median duration of intensive care unit (ICU) stay was 2days and there was 1 mortality. At twelve months follow up, more than 90% of surviving patients were in NYHA class I or II.

Pericardiectomy offers symptomatic relief to patients with constrictive pericarditis. Early identification of this disease would prevent disease progression and offer improved outcomes.

## Linked entities

- **Diseases:** constrictive pericarditis (MONDO:0006711), diastolic heart failure (MONDO:0006727), acute kidney injury (MONDO:0002492), coagulopathy (MONDO:0001531)

## Full-text entities

- **Diseases:** diastolic heart failure (MESH:D054144), tuberculosis (MESH:D014376), coagulopathy (MESH:D001778), low cardiac output (MESH:D002303), Constrictive pericarditis (MESH:D010494), ascites (MESH:D001201), acute kidney injury (MESH:D058186), pleural effusion (MESH:D010996)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12883962/full.md

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Source: https://tomesphere.com/paper/PMC12883962