# Progress in the Immune Mechanism of Microwave Ablation Therapy for Lung Cancer

## TL;DR

This paper reviews how microwave ablation for lung cancer activates the immune system and may improve treatment when combined with immunotherapy.

## Contribution

The paper provides a comprehensive overview of the immune mechanisms activated by microwave ablation in lung cancer treatment.

## Key findings

- Microwave ablation can induce tumor cell necrosis and activate anti-tumor immune responses.
- MWA modulates the tumor immune microenvironment to potentially trigger distant anti-tumor effects.
- Combining MWA with immunotherapy may produce synergistic effects in treating lung cancer.

## Abstract

微波消融（microwave ablation, MWA）是一种微创的热消融治疗手段，目前已广泛应用于肺癌的局部治疗。MWA不仅能够局部有效地诱导肿瘤细胞坏死，还能通过调控肿瘤免疫微环境（tumor immune microenvironment, TIME）诱发潜在远端效应来激活抗肿瘤免疫效应；此外，MWA联合抗肿瘤免疫药物可能发挥协同效应，这为肺癌患者的治疗提供了新的方向。本文综述了MWA治疗肺癌过程中抗肿瘤免疫反应激活的机制，旨在为肺癌未来的治疗策略提供理论基础和实践指导。