# Fecal Microbiota Transplantation: A Promising Avenue for Lung Cancer Therapy

## TL;DR

Fecal microbiota transplantation (FMT) is being explored as a new way to treat lung cancer by improving the immune system through gut bacteria.

## Contribution

This paper reviews recent advances in using FMT to treat lung cancer by modulating the gut microbiota.

## Key findings

- FMT may enhance host immune responses and improve the tumor immune microenvironment.
- The gut microbiota plays a key role in tumor immunotherapy effectiveness.
- FMT is a promising but still emerging strategy in lung cancer treatment.

## Abstract

随着肺癌治疗的不断发展，手术、放化疗、新辅助治疗、靶向治疗及免疫治疗等主流手段在临床中被广泛应用，但仍存在疗效局限性和明显副作用。近年来，肠道菌群在肿瘤免疫调控中的关键作用日益凸显，其对肿瘤免疫治疗的潜在影响已成为肺癌治疗的新兴研究热点。在此背景下，粪菌移植（fecal microbiota transplantation, FMT）作为一种潜在的免疫调节策略被提出，它通过调控肠道菌群以增强宿主免疫应答，改善肿瘤免疫微环境。本文系统梳理了FMT治疗肺癌的最新研究进展，主要围绕肠道菌群与肺癌的关联性、FMT治疗作用机制及临床应用研究等方面，全面探讨了FMT在肺癌治疗中面临的挑战与应用前景。