# Rare Gram-Negative Spinal Epidural Abscess Due to Klebsiella pneumoniae Bacteremia: A Case Report

**Authors:** Anais Panossian, Timmer Verhaegh, Aram A Namavar

PMC · DOI: 10.7759/cureus.101125 · Cureus · 2026-01-08

## TL;DR

A rare case of spinal infection caused by Klebsiella pneumoniae is reported, emphasizing the need for early detection and treatment.

## Contribution

Highlights a rare Gram-negative cause of spinal epidural abscess and its successful treatment approach.

## Key findings

- A 74-year-old male developed SEA due to K. pneumoniae bacteremia from a urinary tract source.
- The patient was successfully treated with surgery and six weeks of intravenous ceftriaxone.
- The case underscores the importance of considering rare pathogens in spinal infections.

## Abstract

Spinal epidural abscesses (SEA) are rare but potentially devastating infections with high morbidity and mortality. Most often, a SEA is caused by Staphylococcus aureus and, on rare occasions, by Gram-negative bacteria such as Klebsiella pneumoniae. The incidence of SEA appears to be rising due to increased spinal instrumentation and enhanced detection with magnetic resonance imaging (MRI). In this case report, we discuss a case of a 74-year-old male patient with K. pneumoniae bacteremia secondary to a urinary tract source, complicated by lumbar SEA, L4-L5 osteomyelitis, and vertebral fracture requiring urgent decompression. The patient was successfully treated with surgical drainage and six weeks of intravenous ceftriaxone. This case highlights the importance of maintaining a high index of suspicion for rare causative organisms of SEA in patients presenting with systemic infection and back pain.

## Linked entities

- **Chemicals:** ceftriaxone (PubChem CID 5479530)
- **Diseases:** spinal epidural abscess (MONDO:0005752), bacteremia (MONDO:0005229), osteomyelitis (MONDO:0005246)
- **Species:** Klebsiella pneumoniae (taxon 573), Staphylococcus aureus (taxon 1280)

## Full-text entities

- **Diseases:** infections (MESH:D007239), osteomyelitis (MESH:D010019), vertebral fracture (MESH:C535781), Bacteremia (MESH:D016470), systemic infection (MESH:D012141), SEA (MESH:D020802), back pain (MESH:D001416), Klebsiella pneumoniae (MESH:D007710)
- **Chemicals:** ceftriaxone (MESH:D002443)
- **Species:** Staphylococcus aureus (species) [taxon 1280], Klebsiella pneumoniae (species) [taxon 573], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12883242/full.md

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Source: https://tomesphere.com/paper/PMC12883242