# Ureter and bladder malakoplakia: a case report

**Authors:** Yu-Ping Ma, Jian-Guo Zhu, Qian-Ye Yong, Qiong Wang, Hai-Ge Li

PMC · DOI: 10.1093/bjrcr/uaag003 · BJR | Case Reports · 2026-01-19

## TL;DR

This case report describes a rare instance of ureter and bladder malakoplakia in a 60-year-old woman, which was initially mistaken for cancer.

## Contribution

The novelty lies in documenting a rare presentation of malakoplakia involving both the ureter and bladder with renal failure.

## Key findings

- Computed tomography and MRI showed thickened ureteral and bladder walls with intraluminal masses.
- Histopathology confirmed malakoplakia through the presence of Michaelis–Gutmann bodies.
- The case highlights the importance of distinguishing malakoplakia from urothelial carcinoma.

## Abstract

Malakoplakia (MP) is a rare granulomatous inflammation that primarily affects the urinary system and has a characteristic histological appearance. We report a case of ureteral and bladder MP associated with renal failure that clinically mimicked urothelial carcinoma. A 60-year-old woman presented to our clinic with a one-year history of left flank pain. Computed tomography urography (CTU) and magnetic resonance (MR) imaging revealed asymmetric thickening of the left ureteral and bladder walls, along with polypoid, contrast-enhancing intraluminal masses. The diagnosis was confirmed by histopathological evaluation, which demonstrated the pathognomonic Michaelis–Gutmann bodies.

## Linked entities

- **Diseases:** malakoplakia (MONDO:0018913), renal failure (MONDO:0001106), urothelial carcinoma (MONDO:0040679)

## Full-text entities

- **Diseases:** granulomatous inflammation (MESH:D007249), flank pain (MESH:D021501), MP (MESH:D008287), urothelial carcinoma (MESH:D014523), renal failure (MESH:D051437)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12883084/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12883084/full.md

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Source: https://tomesphere.com/paper/PMC12883084