# Meyerson’s Phenomenon Surrounding a Seborrheic Keratosis: A Case Report

## TL;DR

A rare immune reaction called Meyerson’s phenomenon occurred around a seborrheic keratosis that had been inactive for 25 years.

## Contribution

This case report documents MP surrounding a seborrheic keratosis, a rare occurrence with unknown causes.

## Key findings

- Meyerson’s phenomenon occurred around a seborrheic keratosis after 25 years of inactivity.
- The exact cause and triggers of Meyerson’s phenomenon remain unknown.
- Treatment options include topical steroids or removal of the inciting lesion.

## Abstract

Meyerson’s phenomenon (MP) is a rare immune-mediated local eczematous reaction that surrounds a pre-existing lesion, including (but not limited to) melanocytic nevi, vascular malformations, nevus sebaceus, and melanoma. We report a case of MP surrounding a seborrheic keratosis that had been non-reactive for the previous 25 years. The exact pathophysiology and antigenic triggers remain unknown. Topical steroids are commonly used to treat MP. However, removal of the inciting lesion may also provide resolution.