# The Combined Konno-Nicks Procedure for Severely Stenotic Aortic Root and Left Ventricular Outflow Tract

**Authors:** Masaru Matsuda, Shin Yajima, Daisuke Yoshioka, Kazuo Shimamura, Ai Kawamura, Takuji Kawamura, Yusuke Misumi, Shunsuke Saito, Shigeru Miyagawa

PMC · DOI: 10.1016/j.jaccas.2025.106544 · JACC Case Reports · 2026-01-28

## TL;DR

A combined surgical procedure successfully enlarged a patient's aortic root and left ventricular outflow tract to prevent mismatch with a new heart valve.

## Contribution

The combined Konno-Nicks procedure is shown to effectively address prosthetic valve dysfunction with severe subvalvular stenosis.

## Key findings

- The combined Konno-Nicks procedure successfully enlarged the annulus and left ventricular outflow tract.
- Postoperative imaging confirmed effective valve enlargement and preserved function.
- This approach prevents prosthesis-patient mismatch in patients with a small annulus and subvalvular stenosis.

## Abstract

Patients with a small aortic root and subvalvular stenosis are at risk of prosthesis-patient mismatch, making annular and left ventricular outflow tract (LVOT) enlargement essential.

We herein report the case of a 41-year-old woman with prosthetic valve dysfunction and severe LVOT obstruction due to pannus formation in whom a 12-mm sizer could not be passed. Redo aortic valve replacement with the combined Konno-Nicks procedure successfully enlarged the annulus and LVOT, enabling the implantation of a 4-size larger prosthesis based on intraoperative sizer measurements. Postoperative echocardiography and computed tomography confirmed effective valve enlargement and preserved valve function.

Combined anterior-posterior enlargement can be valuable for redo aortic valve replacement in patients with a small annulus and subvalvular stenosis to prevent prosthesis-patient mismatch.

The combined Konno-Nicks procedure can effectively relieve prosthetic valve dysfunction with severe subvalvular stenosis by enabling larger prosthesis implantation.

## Full-text entities

- **Diseases:** thromboembolism (MESH:D013923), coronary ostial injury (MESH:D003323), stenosis (MESH:D003251), hypertension (MESH:D006973), dyspnea (MESH:D004417), prosthetic valve stenosis (MESH:D001024), intraventricular defect (MESH:D006345), aortic regurgitation (MESH:D001022), PVD (MESH:D006349), Subvalvular stenosis (MESH:D001020), LVOT obstruction (MESH:D000092242), atrioventricular block (MESH:D054537), adhesions (MESH:D000267), mitral and tricuspid regurgitation (MESH:D014262), SVG (MESH:D055589), diabetes mellitus (MESH:D003920), chest pain (MESH:D002637), ischemia (MESH:D007511), chronic kidney disease (MESH:D051436), aortic valve disease (MESH:D000082862), coronary artery stenosis (MESH:D023921), myocardial ischemia (MESH:D017202), infective endocarditis (MESH:D004696), PG (MESH:D000141)
- **Chemicals:** Carpentier (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12882681/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12882681/full.md

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Source: https://tomesphere.com/paper/PMC12882681