# Complex Aortic Graft Infection with Giant Collection after Bentall-Bono Surgery: Diagnostic and Therapeutic Challenges

**Authors:** Fátima Sol Cabrera, Pau Rello Sabate, Filipa Xavier Valente, Nuria Fernandez-Hidalgo, Nuria Vallejo Camazón, Albert Roque, Gisela Teixidó-Taura, Jose F. Rodriguez-Palomares

PMC · DOI: 10.1016/j.jaccas.2025.106723 · JACC Case Reports · 2026-01-28

## TL;DR

This case study describes a rare and complex aortic graft infection following heart surgery, emphasizing the challenges in diagnosis and the importance of timely treatment.

## Contribution

The paper presents a unique case of AGI with a large collection after Bentall-Bono surgery, highlighting diagnostic and therapeutic challenges.

## Key findings

- The patient's infection was diagnosed using multimodality imaging and blood cultures, revealing a heterogeneous perigraft collection.
- Urgent graft replacement using the hemi-Cabrol technique led to an uncomplicated recovery.
- Early recognition and surgical intervention are critical for improving outcomes in AGI.

## Abstract

Aortic graft infection (AGI) is a rare but life-threatening complication after aortic root surgery, particularly when postoperative collections are present.

A 49-year-old man developed progressive perigraft enlargement followed by fever and chest pain 8 months after Bentall-Bono surgery. He had recently undergone a dental procedure without antibiotic prophylaxis. Blood cultures grew Enterococcus faecalis, and transesophageal echocardiography revealed a heterogeneous perigraft collection with communication to the aortic lumen, as well as graft vegetations and partial suture dehiscence. These findings fulfilled the Management of Aortic Graft Infection Collaboration criteria for AGI. The patient underwent urgent graft replacement using a hemi-Cabrol technique, with an uncomplicated postoperative course.

This case illustrates the diagnostic complexity of AGI in patients with altered postsurgical anatomy, where distinguishing infection from chronic collections is challenging. It highlights the pivotal role of multimodality imaging and coordinated multidisciplinary management.

Early recognition and timely surgical intervention are essential to improving outcomes in AGI.

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** genetic aortopathies (MESH:D030342), hypotension (MESH:D007022), tricuspid regurgitation (MESH:D014262), toxicity (MESH:D064420), B (MESH:D006509), infectious disease (MESH:D003141), anemia (MESH:D000740), Hemorrhagic left hemispheric stroke (MESH:D002544), hypertension (MESH:D006973), hemorrhagic stroke (MESH:D000083302), dyspnea (MESH:D004417), pericardial effusion (MESH:D010490), stroke (MESH:D020521), anastomotic dehiscence (MESH:D057868), Aortic Graft Infection (MESH:D007239), abscess (MESH:D000038), Dyslipidemia (MESH:D050171), inflammation (MESH:D007249), Prosthetic valve endocarditis (MESH:D004696), right bundle branch block (MESH:D002037), rupture (MESH:D012421), aortic dissection (MESH:D000784), Arterial hypertension (MESH:D000081029), fever (MESH:D005334), left ventricular hypertrophy (MESH:D017379), vegetation (MESH:D018458), dehiscence (MESH:D013529), chest pain (MESH:D002637), atrial fibrillation (MESH:D001281), leak (MESH:D019559), Aortic pseudoaneurysm (MESH:D017541), aortic graft (MESH:D055589)
- **Chemicals:** creatinine (MESH:D003404), Cabrol (-), 18F-fluorodeoxyglucose (MESH:D019788), ampicillin (MESH:D000667), ceftriaxone (MESH:D002443), urea (MESH:D014508), oxygen (MESH:D010100)
- **Species:** Staphylococcus aureus (species) [taxon 1280], Enterococcus faecalis (species) [taxon 1351], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12882652/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12882652/full.md

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Source: https://tomesphere.com/paper/PMC12882652