# Assessing Health Care Professionals’ Perceptions of a New System in Clinical Workflows: Systems Engineering Initiative for Patient Safety–Based Consensual Qualitative Research

## TL;DR

This study explores how healthcare professionals view a new AI system for surgical blood ordering, highlighting the need for workflow integration and organizational support to ensure safety and effectiveness.

## Contribution

The study provides novel preimplementation insights into the sociotechnical factors affecting AI-enabled transfusion CDSS adoption in clinical settings.

## Key findings

- pMSBOS-TS could reduce unwarranted variation in blood ordering if the system is reliable and well-integrated into EHR workflows.
- Participants expressed concerns about increased verification burden and communication bottlenecks between clinical units and the blood bank.
- Organizational culture and governance were seen as critical to determining the system's impact on workload and blood product waste.

## Abstract

Artificial intelligence (AI)–enabled clinical decision support systems (CDSSs) are increasingly embedded within electronic health record (EHR) environments; however, their introduction can disrupt existing workflows and raise patient safety concerns, particularly in high-stakes settings such as surgical transfusion. Limited qualitative evidence exists regarding how frontline professionals anticipate the clinical, organizational, and workflow implications of such systems before wider deployment.

This study aims to qualitatively examine the anticipated clinical, organizational, and workflow-level implications of implementing personalized Maximum Surgical Blood Order Schedule—Thoracic Surgery (pMSBOS-TS), an AI-enabled CDSS for personalized surgical blood ordering, before large-scale deployment.

We conducted a consensual qualitative study with 14 multidisciplinary health care professionals involved in transfusion-related tasks at a large tertiary hospital. Following 1 pilot focus group to refine the interview guide and workflow diagram, 2 semistructured focus group discussions were held with 14 participants (5 physicians, 6 nurses, and 3 blood bank staff). Transcripts were analyzed using the Systems Engineering Initiative for Patient Safety (SEIPS) 101 framework, focusing on People, Environment, Tools, and Tasks, and were supported by task- and workflow-based analyses of transfusion processes. Member checking was conducted with participants and external clinicians to enhance validity.

A total of 189 semantic units and 61 core ideas were identified across 18 subdomains and 7 overarching domains. Participants anticipated that pMSBOS-TS could reduce unwarranted variation in blood ordering and planning, provided that algorithmic performance is reliable and the interface is tightly integrated into existing EHR workflows. At the same time, they expressed concerns regarding increased verification burden, system limitations in unexpected clinical scenarios, and potential communication bottlenecks between clinical units and the blood bank. Organizational culture, governance structures, and local transfusion logistics were viewed as critical determinants of whether the system would reduce or inadvertently increase workload and blood product waste.

This preimplementation, SEIPS-based qualitative evaluation suggests that the successful adoption of an AI-enabled transfusion CDSS depends not only on predictive performance but also on sociotechnical readiness, including user trust, workflow fit, and organizational support. These findings provide practice-based insights to inform staged implementation, training, and governance strategies aimed at safely integrating predictive transfusion CDSSs into EHR-supported surgical workflows.