# Sciatic Schwannoma in a Patient with Neurofibromatosis Type 1: A Report of a Minimally Invasive Surgical Technique and Review of the Literature

**Authors:** Eric O Sarpong, Ramin Rahmanzade, Adolf Mueller, Hannes Egermann, Attila Sarkadi

PMC · DOI: 10.7759/cureus.101058 · Cureus · 2026-01-07

## TL;DR

This paper describes a minimally invasive surgical technique for removing a sciatic schwannoma in a patient with neurofibromatosis type 1.

## Contribution

The novelty is the use of a minimally invasive approach for sciatic schwannoma resection in NF1.

## Key findings

- Sciatic schwannomas are rare in NF1 patients and typically cause sciatica in less than 1% of cases.
- A minimally invasive technique was successfully used for resection in this case.
- The clinical and imaging features of these tumors were reviewed.

## Abstract

Schwannomas rarely occur in patients with neurofibromatosis type 1 (NF1). A sciatic schwannoma (SS) is the cause of sciatica in less than one percent of cases. These tumors are traditionally resected by the transgluteal approach, gaining access to the tumor through a large incision. Herein, we report a minimally invasive resection of an SS in a patient with NF1, who presented with typical sciatica four months after resection of a lumbar schwannoma. The clinical and imaging characteristics of these tumors are also reviewed.

## Linked entities

- **Diseases:** neurofibromatosis type 1 (MONDO:0018975), sciatica (MONDO:0024333)

## Full-text entities

- **Genes:** NF1 (neurofibromin 1) [NCBI Gene 4763] {aka NFNS, VRNF, WSS}
- **Diseases:** SS (MESH:D009442), tumor (MESH:D009369), sciatica (MESH:D012585)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC12881864/full.md

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Source: https://tomesphere.com/paper/PMC12881864