# Long‐Term Survival With Minimum Side‐Effects in a Post‐Op Case of Carcinoma Esophagus With Multiple Recurrences in Mediastinum Treated With Radical Re‐Radiotherapy in Mediastinum—A Case Report

**Authors:** Ajay Kumar Choubey, Pritam Mondal, Shubham Dokania, Sambit Swarup Nanda, Shreya Jain, Minesh Patel, Ashutosh Mukherji, Satyajit Pradhan

PMC · DOI: 10.1002/ccr3.71520 · Clinical Case Reports · 2026-02-06

## TL;DR

A patient with multiple recurrences of esophageal cancer in the mediastinum was successfully treated with re-radiotherapy, achieving long-term survival with minimal side effects.

## Contribution

This case report demonstrates the safety and efficacy of re-radiotherapy for managing multiple mediastinal recurrences in esophageal cancer.

## Key findings

- Re-radiotherapy in the mediastinum was safely administered after multiple recurrences.
- The patient achieved long-term survival with minimal late morbidity.
- An acceptable time gap between radiotherapy sessions was crucial for successful treatment.

## Abstract

Loco‐regional recurrence after radical surgery in esophageal cancer is common. However, there is no universally accepted guideline for managing such loco‐regional recurrences. Even after multiple local recurrences in the mediastinum, a patient can consolidate safely by re‐radiotherapy in the mediastinal region with minimal late morbidity by judicious use of radiotherapy, if there is an acceptable time gap between two radiotherapy periods.

Summary of the case with time point of recurrences and treatment received.

## Linked entities

- **Diseases:** esophageal cancer (MONDO:0007576)

## Full-text entities

- **Diseases:** Carcinoma Esophagus (MESH:D004938)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12881697/full.md

## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC12881697/full.md

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Source: https://tomesphere.com/paper/PMC12881697