# Exploring the influence of COVID-19 stress on mental health among international undergraduate and graduate students: A mixed-methods approach

**Authors:** Chinyere N. Reid, Jason W. Beckstead, Abraham A. Salinas-Miranda, Mukhtiar Baig, Mukhtiar Baig, Mukhtiar Baig

PMC · DOI: 10.1371/journal.pone.0336446 · PLOS One · 2026-02-06

## TL;DR

This study explores how stress from the COVID-19 pandemic affects mental health differently in international undergraduate and graduate students in the US.

## Contribution

The study reveals that education level moderates the relationship between pandemic stress and anxiety, but not depression, among international students.

## Key findings

- COVID-19 stress was significantly linked to anxiety and depression in international students.
- Education level moderated the relationship between pandemic stress and anxiety, but not depression.
- Stressors included academic performance, financial issues, travel constraints, social isolation, and grief.

## Abstract

International college students in the United States are at increased risk of developing mental health disorders and are less likely to seek mental health services. However, little is known about the effects of stress during the COVID-19 pandemic on the mental health of international undergraduate students compared to their graduate counterparts studying in the US. This study examined the associations between COVID-19 stress, anxiety, and depression and whether education level moderates these associations in international undergraduate and graduate students. A cross-sectional online survey containing psychometric scales and open-ended questions was completed by 219 international undergraduate and graduate students. Validated psychometric scales used included the Depression, Anxiety, and Stress Scale (DASS-21), COVID-19 Stress Scale (CSS), and Perceived Stress Scale 4 (PSS-4). Path analysis was used to assess whether education level moderated the relationships between COVID-19 stress and anxiety and depression. Applied thematic analysis was conducted to qualitatively determine COVID-19-related stressors affecting students’ mental health. We found that COVID-19 stress was significantly associated with students’ anxiety and depression, and education level moderated the relationship between COVID-19 stress and anxiety, but not depression. Major themes of COVID-19-related stressors affecting mental health included academic performance, financial difficulties, travel constraints, social isolation, and grief. Findings highlighted the influence of stress during the COVID-19 pandemic on the mental health of international students studying in the US. Graduates and undergraduates experienced stress differently, particularly related to anxiety. Additionally, pandemic-related stressors were multifaceted in nature. Adequate mental health interventions and support tailored for graduates and undergraduates are needed to address students affected during global crises.

## Full-text entities

- **Diseases:** illness (MESH:D002908), Depression (MESH:D003866), COVID (MESH:D000086382), headaches (MESH:D006261), Death (MESH:D003643), anhedonia (MESH:D059445), anxiety symptoms (MESH:D001008), sleep disorder (MESH:D012893), allergy (MESH:D004342), skin disease (MESH:D012871), Anxiety (MESH:D001007), compulsive checking behaviors (MESH:D003193), anxious affect (MESH:D019964), traumatic stress (MESH:D040921), infection (MESH:D007239), panic attacks (MESH:D016584), loss of concentration (MESH:C567712), inertia (MESH:D014593), dysphoria (MESH:D019052), mental disorders (MESH:D001523), Mental health (OMIM:603663), infectious (MESH:D003141), COVID Stress (MESH:C000711430), loss (MESH:D016388)
- **Chemicals:** PONE-D-25-25688R1 (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Cell lines:** Line 229 — Canis lupus familiaris (Dog), Canine mammary carcinoma, Cancer cell line (CVCL_L334)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12880682/full.md

## References

54 references — full list in the complete paper: https://tomesphere.com/paper/PMC12880682/full.md

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Source: https://tomesphere.com/paper/PMC12880682