# Evaluating acceptability of the Inpatient Mental Health Pharmaceutical Assessment and Care Tool (IMPACT): A multi-site study in the United Kingdom

**Authors:** Fatima Q. Alshaikhmubarak, Richard N. Keers, Petra Brown, Penny J. Lewis, Yaser Mohammed Al-Worafi, Yaser Mohammed Al-Worafi, Yaser Mohammed Al-Worafi

PMC · DOI: 10.1371/journal.pone.0341776 · PLOS One · 2026-02-06

## TL;DR

This study evaluates how well pharmacy teams in the UK accept a new tool for identifying high-risk mental health patients.

## Contribution

The first evaluation of the IMPACT tool's acceptability among mental health inpatient pharmacy teams using qualitative methods.

## Key findings

- The IMPACT tool was viewed as self-explanatory and effective by most participants.
- Some pharmacy technicians faced challenges due to unfamiliar clinical criteria.
- Modifications to the tool based on feedback were well-received and improved its usability.

## Abstract

The Inpatient Mental Health Pharmaceutical Assessment and Care Tool (IMPACT) was developed to assist pharmacy teams in identifying high risk patients for early intervention. Evaluation of the IMPACT tool is important to ensure its feasibility and effectiveness. This study reports the first evaluation of the IMPACT tool aiming to explore its acceptability by mental health inpatient pharmacy teams using an iterative qualitative approach.

Between October 2024 and February 2025, pharmacy staff from five National Health Service (NHS) organisations retrospectively applied the IMPACT tool on patients that they had provided pharmaceutical care to, completed a reflection sheet, and attended an online focus group. Training was delivered to participants before initiating the study and the Theoretical Framework of Acceptability guided the content and analysis of the focus groups.

Four focus groups and one dual interview were conducted with 12 pharmacists and 5 pharmacy technicians. The tool was viewed as self-explanatory and effective. Most participants were confident using the tool, though some pharmacy technicians reported difficulties due to clinical criteria (e.g., blood tests interpretation) that was not part of their usual duties. Following the first focus group, some changes were made such as clarifying or combining some risk-indicators. These changes were well-received by subsequent participants and recommendations and insights gained from all participants assisted in improving the tool.

This study revealed that the IMPACT tool was acceptable by pharmacy team members and resulted in a refined version. Future work should further explore the tool’s feasibility and impact using mixed methods approaches.

## Full-text entities

- **Genes:** F3 (coagulation factor III, tissue factor) [NCBI Gene 2152] {aka CD142, TF, TFA}, PRL (prolactin) [NCBI Gene 5617] {aka GHA1, pPRL}
- **Diseases:** learning disabilities (MESH:D007859), uncontrolled diabetes (MESH:D003920), dementia (MESH:D003704), Chronic kidney Disease (MESH:D051436), substance abuse (MESH:D019966), infection (MESH:D007239), CKD (MESH:D012080), Mental (MESH:D008607), uncontrolled blood pressure (MESH:D006973), psychiatric (MESH:D001523), eating disorders (MESH:D001068)
- **Chemicals:** Al (MESH:D000535), PONE-D-25-34054R1 (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12880654/full.md

## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC12880654/full.md

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Source: https://tomesphere.com/paper/PMC12880654