# Open source inert gas glove box

**Authors:** Mottaghi Maryam, M. Pearce Joshua

PMC · DOI: 10.1016/j.ohx.2025.e00702 · HardwareX · 2025-09-19

## TL;DR

This paper introduces a low-cost, customizable open-source glove box that can maintain an inert atmosphere for scientific experiments.

## Contribution

The novel contribution is a validated open-source design for an inert gas glove box that is highly cost-effective and customizable.

## Key findings

- The open source glove box can reduce oxygen levels to 19 ppm using inert gas.
- The design achieves over 95% economic savings compared to commercial systems.
- The device is portable and allows for customizable dimensions and transfer chambers.

## Abstract

A glove box is a controlled environment used for a wide range of scientific experiments. While glove boxes provide significant advantages, their high economic costs ranging from over $1,000 to over $15,000 limits their accessibility in under-resourced labs. There are lower-cost DIY designs available on the internet, but they have not been well characterized nor validated. To overcome these limitations, in this study, an open source glove box design is developed for scientific applications using readily available components and digital distributed manufacturing using open-source RepRap-class 3D printers. The ability of the glove box to hold an inert atmosphere is quantified using an oxygen analyzer. The open source glove box can be customized to the dimensions of the user and the volume of the experiment. The design also enables the use of customizable transfer chambers that can be adjusted based on the scientific application. The open source glove box is built from a low-cost enclosure while preventing contamination. The highly portable device can reduce oxygen down to 19 ppm using an inert gas. The economic savings of the validated device compared to proprietary systems is over 95 %.

## Full-text entities

- **Chemicals:** oxygen (MESH:D010100)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12880624/full.md

## Figures

13 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12880624/full.md

## References

43 references — full list in the complete paper: https://tomesphere.com/paper/PMC12880624/full.md

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Source: https://tomesphere.com/paper/PMC12880624