# Correlation between glycemic control and left ventricular diastolic dysfunction in type 2 diabetes

**Authors:** Aparnna Unnikrishnan Nair, Sorabh Sharma, Asma Aara Younus, Jonathan Roy Varghese, Shanmukha Koppolu, Sharik Mehraj Patloo

PMC · DOI: 10.6026/973206300214084 · Bioinformation · 2025-11-15

## TL;DR

This study explores how poor blood sugar control in type 2 diabetes affects heart function, specifically diastolic dysfunction.

## Contribution

The paper investigates the relationship between HbA1c levels and left ventricular diastolic dysfunction in type 2 diabetes patients.

## Key findings

- Poor glycemic control is associated with increased left ventricular diastolic dysfunction in T2DM patients.
- Higher HbA1c levels correlate with more severe cardiac dysfunction in type 2 diabetes.
- Early screening for cardiac issues may reduce long-term cardiovascular risks in poorly controlled diabetic patients.

## Abstract

Type 2 diabetes mellitus (T2DM) has been linked to higher cardiovascular morbidity and left ventricular diastolic dysfunction (LVDD).
The potential influence of the severity of cardiac dysfunction T2DM patients may depend on diabetes control measures and HbA1c concentration
levels. Therefore, it is of interest to determine the relationship between HbA1c and LVDD in patients with type 2 DM by measurement
echocardiographic parameters, along diastolic dysfunction and poor glycemic control as indications of the presence of an association.
Early cardiac screening interventions may lead to lower long-term cardiovascular morbidity in population studies of poorly controlled
diabetic patients.

## Linked entities

- **Diseases:** Type 2 diabetes mellitus (MONDO:0005148)

## Full-text entities

- **Diseases:** T2DM (MESH:D003924), diabetes (MESH:D003920), type 2 DM (MESH:D009223), LVDD (MESH:D018487), cardiac dysfunction (MESH:D006331)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12880167/full.md

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Source: https://tomesphere.com/paper/PMC12880167